肉蓯蓉Cistanches Herba為我國傳統(tǒng)大宗藥材，臨床應用廣泛，素有“沙漠人參”之稱。已在2023年通過食用安全性評價，正式被國家衛(wèi)生健康委員會列入藥食同源物質(zhì)目錄。研究發(fā)現(xiàn)，肉蓯蓉屬植物富含多糖、有機酸、蛋白質(zhì)、膳食纖維、礦質(zhì)元素、氨基酸、維生素等初生代謝成分，及苯乙醇苷類、環(huán)烯醚萜苷類、木脂素類等次生代謝成分，具有神經(jīng)保護、潤腸通便、免疫調(diào)節(jié)、益腎保肝、抗骨質(zhì)疏松、抗腫瘤、抗炎、抗氧化等藥理活性。通過對肉蓯蓉屬植物的初生代謝成分、次生代謝成分、藥理活性及藥食兩用等進行綜述，為肉蓯蓉活性成分的臨床應用、藥食同源開發(fā)及生物資源的綜合利用提供參考。

Roucongrong (Cistanches Herba), a traditional Chinese medicinal material with extensive clinical applications, is known as the “Ginseng of the Desert”. In 2023, it has passed the evaluation of food safety and has been officially included in the directory of substances that are the same origin as food and medicine by the National Health Commission of China. It has found that plants of genus Cistanche are rich in a variety of primary metabolites, such as polysaccharides, organic acids, proteins, dietary fiber, mineral elements, amino acids, and vitamins, as well as secondary metabolites like phenylethanoid glycosides, iridoid glycosides, and lignans, etc. These compounds exhibit a range of pharmacological activities, including neuroprotection, moistening the intestines and relieving constipation, immune regulation, kidney and liver protection, anti-osteoporosis, anti-tumor, anti-inflammatory, and antioxidant effects. The primary metabolites, secondary metabolites, pharmacological activities and dual-use of Cistanchis plants were systematically reviewed in order to provide references for the clinical application, the development of medicine and food homology, and the comprehensive utilization of biological resources of Cistanches Herba active ingredients.

甘肅省科技計劃項目（20JR10RA355）；甘肅省衛(wèi)生健康行業(yè)科研項目（GSWSKY2022-27）；國家中醫(yī)優(yōu)勢?？平ㄔO(shè)項目—腦病臨床醫(yī)學中心（甘衛(wèi)中醫(yī)函[2023]63號）