厚樸藥材具有止咳祛痰作用，對(duì)氣管平滑肌具有收縮和舒張的雙向作用。厚樸酚及和厚樸酚是疏水性烯丙基聯(lián)苯酚類結(jié)構(gòu)的同分異構(gòu)體，也是厚樸產(chǎn)生呼吸系統(tǒng)藥理作用的主要活性成分。厚樸酚及和厚樸酚都具有松弛氣管平滑肌作用和平喘作用，都具有肺保護(hù)作用和對(duì)抗各種病理因子引起的肺損傷作用。厚樸酚及和厚樸酚還具有廣譜的抗病毒、抗菌和細(xì)胞保護(hù)作用，尤其適用于具有基礎(chǔ)疾病的各種肺損傷，以期被開發(fā)為新藥供臨床利用。

Magnoliae Officinalis Cortex has antitussive and expectorant effects, and dual-directional action on contraction and relaxation of bronchial smooth muscle. Magnolol and honokiol are hydrophotic isomer of propenyl biphenol-type structure, and major active components of Magnoliae Officinalis Cortex in pharmacologic action of respiratory system. Magnolol and honokiol have relaxation of trachea smooth muscle and antiasthmatic effect, have lung-protection, and antagonize lung injury induced by various pathological factors. Magnolol and honokiol have broad-spectrum antibacterial and anti-viral effects, and cellular protection, too. Magnolol and honokiol to prevention and treatment for various pneumonia with basic disease were recommended, intended to be developed as a new drug for clinical use.

R285.5