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[摘要]
目的 探究預防性靜滴鉀離子、鎂離子對急性心梗后并發(fā)室性心律失常的預防作用。方法 選擇2015年1月-2018年1月于西寧市第一人民醫(yī)院進行治療的78例急性心肌梗死患者為研究對象,按照隨機數(shù)字表法將其均分為觀察組與對照組,每組各39例患者。對照組患者進行常規(guī)急性心梗治療,觀察組患者在對照組基礎上加用門冬氨酸鉀鎂進行治療,對比兩組治療有效率,對比兩組治療前后血液流變學指標纖維蛋白原(Fib)、凝血酶原時間(PT)、血小板計數(shù)(Plt),對比兩組治療期間不良反應發(fā)生率及心律失常發(fā)生率。結果 治療后,觀察組患者治療有效率為87.18%,對照組為76.92%,兩組對比差異具有統(tǒng)計學意義(P<0.05)。治療前兩組患者Fib、PT以及Plt水平對比差異不具有統(tǒng)計學意義;治療后,兩組患者Plt及Fib水平低于治療前,PT水平高于治療前,差異有統(tǒng)計學意義(P<0.05);治療后觀察組患者Plt及Fib水平低于對照組,PT水平高于對照組(P<0.05)。觀察組患者不良反應發(fā)生率稍高于對照組,但對比差異不具有統(tǒng)計學意義。觀察組心律失常發(fā)生率為7.69%,對照組為15.38%,兩組對比差異具有統(tǒng)計學意義(P<0.05)。結論 預防性靜滴鉀離子與鎂離子能夠顯著降低急性心?;颊咝穆墒С0l(fā)生率,同時有利于提高治療有效率,改善其血流變指標,且安全性較高。
[Key word]
[Abstract]
Objective To explore the preventive effect of intravenous potassium ion and magnesium ion on ventricular arrhythmia after acute myocardial infarction. Methods 78 patients with acute myocardial infarction who were treated in Xining No.1 People's Hospital from January 2015 to January 2018 were divided into observation group and control group according to random number table method, each group had 39 patients. Patients in the control group were treated with routine acute myocardial infarction treatment. The observation group was treated with potassium aspartate and magnesium aspartate on the basis of the control group. And the effective rate was compared between two groups. The hemorheological indexes, such as Fib, PT, and Plt were compared before and after treatment in two groups. The incidence of adverse reactions and arrhythmias during treatment were compared between two groups. Results After treatment, the effective rate was 87.18% in the observation group and 76.92% in the control group, the difference between the two groups was statistically significant (P<0.05). Before treatment, there was no significant difference in the levels of Fib, PT and Plt between two groups. After treatment, the levels of Plt and Fib in the observation group were decreased, and PT levels were higher than before treatment, with statistically significant differences in the same group (P<0.05). After treatment, Plt and Fib levels in the observation group were lower than those in the control group, and PT levels were higher than those in the control group (P<0.05). The incidence of adverse reactions in the observation group was slightly higher than that in the control group, but the difference was not statistically significant. The incidence of arrhythmia in the observation group was 7.69%, and that in the control group was 15.38% (P<0.05). Conclusion Preventive intravenous drip of potassium ion and magnesium ion can significantly reduce the incidence of arrhythmia in patients with acute myocardial infarction, at the same time, it is conducive to improve the treatment efficiency, improve its hemorheological indicators, and is safe.
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