目的 探討氨茶堿治療小兒反復(fù)氣管支氣管炎非急性期的效果。方法 2011年1月-2016年12月選擇在西安市中心醫(yī)院診治的小兒反復(fù)氣管支氣管炎非急性期患兒210例作為研究對(duì)象，根據(jù)隨機(jī)信封抽簽原則分為觀察組與對(duì)照組各105例，對(duì)照組給予常規(guī)治療，觀察組在對(duì)照組基礎(chǔ)上給予氨茶堿靜滴治療，兩組都治療觀察7 d。比較兩組臨床療效，觀察兩組的咳嗽、肺部羅音、喘息等癥狀消失時(shí)間，比較兩組的肺功能和生活質(zhì)量評(píng)分。結(jié)果 對(duì)照組總有效率為89.5%，觀察組的總有效率為98.1%，觀察組的總有效率明顯高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組的咳嗽消失時(shí)間、肺部羅音消失時(shí)間與喘息消失時(shí)間都明顯優(yōu)于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組與對(duì)照組治療后的FEV1值分別為（87.22±6.39）%和（78.20±7.38）%，都明顯好于治療前的（67.20±7.20）%和（66.98±6.82）%，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組治療后的FEV1值也明顯高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組與對(duì)照組治療后的生活質(zhì)量評(píng)分分別為（36.44±5.14）分和（42.30±5.00）分，觀察組評(píng)分低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 氨茶堿治療反復(fù)氣管支氣管炎非急性期能促進(jìn)臨床癥狀的恢復(fù)，改善肺功能，促進(jìn)提高治療效果，改善總體生活質(zhì)量，有很好的應(yīng)用價(jià)值。

Objective To investigate the effects and mechanism aminophylline in the treatment of patients with non acute stage recurrent bronchitis.Methods From February 2013 to December 2016, 120 cases of children with non acute stage recurrent bronchitis in our hospital were selected as the research object, all the cases were divided into observation group and control group with 105 cases in each group accorded to the random draw envelope principle, the control group was given routine treatment, the observation group was given inhalation aminophylline treatment based on the treatment in control group, two groups observation on the treatment of 7 d.Results The total effective rate of the control group was 89.5%, the total effective rate of the observation group was 98.1%, and the total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The cough disappeared time, pulmonary rales disappeared time and wheezing disappearance time in the observation group were significantly better than the control group (P < 0.05). The FEV1 values in the observation group and the control group after treatment were (87.22 ±6.39)% and (78.20 ±7.38)% that were significantly better than before treatment of (67.20 ±7.20)% and (66.98 ±6.82)% (P < 0.05), the observation group after treatment FEV1 value was higher than the control group (P < 0.05). The quality of life scores of the observation group and the control group after treatment were (36.44 ±5.14) and (42.30 ±5.00) points respectively, the scores of the observation group were lower than those of the control group (P < 0.05).Conclusion Aminophylline can promote the recovery of clinical symptoms in the treatment of patients with non acute stage recurrent bronchitis, it can improve lung function and the therapeutic effect, it also can improve the overall quality of life.