腫瘤的發(fā)病率在逐年增高，且發(fā)病機(jī)制復(fù)雜，變異度高，是影響人類健康和生活質(zhì)量的重大疾病?？鼓[瘤的相關(guān)研究也一直是醫(yī)學(xué)研究領(lǐng)域的重點(diǎn)、難點(diǎn)。而隨著代謝組學(xué)的興起，腫瘤重編程概念的提出，氨基酸代謝已成為抗腫瘤領(lǐng)域相關(guān)研究的重要切入點(diǎn)，用于闡明腫瘤發(fā)生機(jī)制、發(fā)現(xiàn)腫瘤治療新靶點(diǎn)。對(duì)氨基酸代謝和腫瘤、腫瘤營養(yǎng)、腫瘤微環(huán)境、腫瘤相關(guān)基因、抑癌因子、中藥療法的關(guān)系進(jìn)行綜述，為腫瘤臨床治療以及進(jìn)一步研究提供依據(jù)和參考。

Recently, with the development of medical technology, more and more diseases have been successfully compromised. However, the incidence of cancer is increasing year by year with complicated pathogenesis and high variability, which is still a major risk factor affecting humans health and the quality of life. Therefore, tumor related research has always been the focus of medical research, and with the new metabonomics, the concept of tumor reprogramming, amino acid metabolism has been widely used in cancer research, to clarify the mechanism of tumorigenesis and found new targets for the treatment of cancer. This article aims to briefly review the research progress of amino acid metabolism in tumor nutrition metabolism, immune microenvironment, mechanism of occurrence and treatment.