目的 觀察貝復(fù)舒滴眼液聯(lián)合玻璃酸鈉滴眼液治療白內(nèi)障術(shù)后角膜水腫的臨床效果。方法 2014年1月-2016年1月選擇在北京市順義區(qū)婦幼保健院診治的白內(nèi)障術(shù)后角膜水腫患者78例，根據(jù)隨機(jī)信封抽簽原則分為觀察組與對(duì)照組各39例，對(duì)照組給予玻璃酸鈉滴眼液治療，觀察組給予貝復(fù)舒滴眼液聯(lián)合玻璃酸鈉滴眼液治療，兩組都連續(xù)治療觀察4周。比較兩組臨床療效、治療前后視力狀況、并發(fā)癥情況及炎癥因子白細(xì)胞介素-6（IL-6）和腫瘤壞死因子-α（TNF-α）水平。結(jié)果 治療后觀察組的有效率（98.7%）明顯高于對(duì)照組（88.5%），差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后觀察組與對(duì)照組的視力明顯好于治療前，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；同時(shí)觀察組治療后的視力明顯好于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組治療期間的新生血管性青光眼、瞳孔區(qū)模性滲出、玻璃體積血等并發(fā)癥發(fā)生率為7.7%，對(duì)照組為9.0%，兩組對(duì)比無(wú)明顯差異。治療后觀察組的淚液IL-6和TNF-α含量明顯低于治療前，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；同時(shí)治療后觀察組的淚液IL-6和TNF-α含量明顯低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 貝復(fù)舒滴眼液聯(lián)合玻璃酸鈉滴眼液治療白內(nèi)障術(shù)后角膜水腫能抑制淚液中炎癥因子的表達(dá)，具有很好的安全性，從而提高治療療效與改善視力。

Objective To observe the clinical efficacy of sodium hyaluronate drops combined with Bei Fu Shu drops in the treatment of corneal edema after cataract surgery.Methods From January 2014 to January 2016, 78 patients with corneal edema after cataract surgery in our hospital for treatment were selected as the research object, all the patients were divided into observation group and control group with 39 cases in each group accorded to the random draw envelope principle. The control group was given sodium hyaluronate drops treatment, the observation group was given Bei Fu Shu drops based in the treatment of the control group, all the patients were treated for 4 weeks.Results After treatment, the effective rate of the observation group and the control group were 98.7% and 88.5% respectively, and the effective rate of the observation group was significantly higher than that of the control group (P< 0.05). After treatment, the visual acuity of the observation group and the control group were significantly better than that before treatment (P< 0.05), and the visual acuity in the observation group after treatment was better than that of the control group (P< 0.05). The complication rate of neovascular glaucoma, pupillary zone effusion and vitreous hemorrhage in the observation group during treatment was 7.7%, so that was 9% in the control group. After treatment, the IL-6 and TNF-α contents of tear in the two groups were significantly lower than that before treatment (P< 0.05), and the IL-6 andIL-6 and TNF-α contents of tear after treatment in the observation group was significantly lower than the control group (P< 0.05).Conclusion Sodium hyaluronate drops combined with Bei Fu Shu drops in the treatment of corneal edema after cataract surgery can inhibit the expression of inflammatory factors in tears and has good safety, which can improve the therapeutic effect and improve the visual acuity.