中藥藥效物質(zhì)基礎(chǔ)研究是中藥現(xiàn)代研究的關(guān)鍵問題,而血清藥物化學(xué)為進(jìn)一步闡明中藥藥效物質(zhì)基礎(chǔ)提供了方法支持,已成為近年來研究中藥及中藥復(fù)方藥效物質(zhì)基礎(chǔ)發(fā)展迅速的方法之一。本文對血清藥物化學(xué)的概念及研究方法進(jìn)行了回顧,綜述近年來其在單味中藥及中藥復(fù)方物質(zhì)基礎(chǔ)研究中的應(yīng)用進(jìn)展以及目前存在的問題,并對血清藥物化學(xué)應(yīng)用于中藥復(fù)方研究的發(fā)展方向進(jìn)行了展望。

Serum pharmacochemistry in recent years has become one of the rapid development methods in research of the pharmacodynamics material basis of Chinese materia medica (CMM) and complex prescription. The concepts and the research models of serum pharmacochemistry were reviewed in this article, the progress on the material basis of traditional Chinese medicine and complex prescription in recent years were summarized, and the future prospects of serum pharmacochemistry applied to CMM were discussed.