中藥提取物的純化工藝直接關系到中藥口服液制劑的質(zhì)量，2010年版《中國藥典》所收載口服液的醇沉除雜法存在生產(chǎn)工時長、有效成分損失大等缺點。陶瓷膜分離技術不僅有分離、濃縮、純化和精制的功能，同時具有生產(chǎn)時間短、有效成分損失小等特點，已作為一項前景十分廣闊的高新技術運用到中藥制劑的生產(chǎn)過程中。陶瓷膜分離技術應用在中藥口服液生產(chǎn)中可縮短生產(chǎn)流程、提高中藥口服液的穩(wěn)定性和安全性，目前已采用多種方法解決膜污染問題，以解決制約其應用的瓶頸問題。

Purification process of herbal extracts is directly related to the quality of oral liquid of Chinese materia medica (CMM). Most of the CMM oral liquid collected in Chinese Pharmacopeia 2010 were made by the method of alcohol precipitation to remove impurities which has some shortcomings, i.e. long working hours and the massive loss of effective components, etc. The ceramic membrane separation technology not only has the functions like separation, concentration, purification, and refining function, but also has the characteristics such as short production time and the small loss of effective components etc. It will have a broad prospect for the application in the production process of Chinese drugs pharmaceutics as a new technology. The ceramic membrane separation technology can shorten the production flow, improve the stability and safety of CMM oral liquid, but the membrane fouling?is the main obstacle to restrict its application, which should be overcome in future.

四川省經(jīng)信委創(chuàng)新能力提升專項（2013NL021）