目的 探討血必凈注射液對慢性阻塞性肺疾病急性加重期（AECOPD）合并呼吸衰竭患者的臨床療效。方法 將58例AECOPD合并呼吸衰竭患者隨機分為治療組31例和對照組27例，對照組給予西醫(yī)常規(guī)治療，治療組在此基礎(chǔ)上加用血必凈注射液50 mL，2次/d，靜脈滴注，療程7 d。觀察2組血氣分析、血清降鈣素原（PCT）濃度變化及脫機成功率、脫機時間。結(jié)果 治療組血氣、PCT改善情況明顯優(yōu)于對照組（P＜0.01），脫機時間明顯短于對照組（P＜0.05），脫機成功率明顯高于對照組（P＜0.01）。結(jié)論 在傳統(tǒng)的西醫(yī)療法基礎(chǔ)上加用血必凈注射液可使AECOPD合并呼吸衰竭患者血清PCT水平快速顯著下降，具有良好的治療作用。PCT濃度與AECOPD的嚴重程度成正相關(guān)性，可以比較客觀地評價其治療效果和預(yù)后。

Objective To evaluate the clinical effect of Xuebijing Injection (XI) on the patients in acute exacerbation period of chronic obstructive pulmonary disease (AECOPD) with respiratory failure. Methods Fifty-eight patients in AECOPD with respiratory failure were randomly divided into the treatment (31 cases) and control (27 cases) groups. With the routine therapy in two groups, the patients in the treatment group were iv dripped with XI, twice daily for 7 d. Using blood gas analysis, the concentration change of serum procalcitonin (PCT), the offline success ratio and offline time were observed. Results The blood gas analysis, the serum PCT level, the offline success ratio, and offline time were improved in the treatment group compared with those of the control group (P < 0.05). Conclusion XI combined with western medicine treatment has a good therapeutic effect on AECOPD.