目的 探索丹參飲口服液的最佳水提工藝。方法 以水提物中有效成分丹參素鈉為指標，采用高效液相色譜法測定丹參素鈉含量，運用正交設計法對丹參飲口服液水提取工藝進行優(yōu)選。結(jié)果 丹參飲口服液最佳水提取工藝為按5倍量處方比例稱取粗碎藥材，浸泡0.5 h，加入10倍量水煎煮3次，每次1.5 h。結(jié)論 采用該水提工藝提取，水提取物中丹參素鈉的收率較高且穩(wěn)定。

Objective To optimize the water extracting process for Selection of Danshen Decoction Oral Liquid. Methods Taking sodium Danshensu as an indicator, HPLC was used to detect the content of sodium Danshensu and orthogonal design to optimize the water extraction process of Danshen Decoction Oral Liquid. Results The optimal extraction process of Danshen Decoction Oral Liquid as follow: The crushed crude traditional Chinese medicinal materials were weighed in a five-fold volume ratio of prescription with soaking for 0.5 h, decocting for three times by ten-fold water, once for 1.5 h. Conclusion Using the water extract process, the yield in the water extract of sodium Danshensu is high and stable.

瀘州市科技局課題（LSCQ《2010》41號）