目的：研究丹紅注射液對大鼠缺血再灌注損傷的保護(hù)作用。方法：采用線栓法建立大鼠腦缺血再灌注模型，觀察丹紅注射液對腦缺血再灌注損傷大鼠的神經(jīng)功能評分、腦組織中一氧化氮合酶（NOS）、一氧化氮（NO）、超氧化物歧化酶（SOD）、丙二醛（MDA）等的影響。結(jié)果：丹紅注射液可顯著降低腦缺血再灌注大鼠的神經(jīng)功能評分，減輕腦組織損傷程度；提高SOD活力，降低MDA和NO、NOS水平。結(jié)論：丹紅注射液對大鼠缺血再灌注損傷具有明顯的保護(hù)作用。

Objective: To investigate the protection of Danhong Injection on the cerebral ischemia-reperfusion injury of rats. Methods: The models of focal brain ischemia-reperfusion injury were prepared by middle cerebral artery occlusion (MCAO) in rats. The effects of Danhong Injection on the cerebral ischemia-reperfusion injury of rats, such as nerve function grade and contents of NOS, NO, SOD, and MDA in brain tissues, were observed. Results: Danhong Injection could decrease the nerve function grade, improve the vigor of SOD, depress the levels of MDA, NO, and NOS. Conclusion: Danhong Injection can protect the brain from ischemia-reperfusion injury in rats.