隨著肺癌相關基因組學研究的深入及高通量測序技術(shù)的發(fā)展，越來越多的驅(qū)動基因在肺癌中被發(fā)現(xiàn)，這為肺癌的精準治療提供了一種新途徑。對近年來肺癌的靶向藥物的作用機制及其耐藥機制的研究進展進行綜述，旨在幫助讀者對肺癌靶向藥物的個體化選擇及耐藥機制有一個全面的了解。

With the development of lung cancer-related genomics research and the development of high-throughput sequencing technology, more and more driving genes are found in lung cancer, which provides a new way for the precise treatment of lung. Research progress on action mechanism of and drug resistance mechanism of molecular targeted drugs for lung cancer are reviewed in this paper, aiming to help readers have a comprehensive understanding of the individualized choice of lung cancer targeted drugs.

重慶醫(yī)科大學附屬永川醫(yī)院青年課題（YJQN2011032）