[關(guān)鍵詞]
[摘要]
腦出血是全球致死致殘的主要病因,發(fā)病機(jī)制復(fù)雜。黃芩苷是黃芩中的主要活性成分,可通過(guò)減輕神經(jīng)炎癥反應(yīng)、減輕氧化應(yīng)激反應(yīng)、抑制神經(jīng)細(xì)胞凋亡、糾正抑制性氨基酸γ-氨基丁酸系統(tǒng)失衡、保護(hù)血腦屏障的完整性治療腦出血??偨Y(jié)了黃芩苷治療腦出血的藥理作用研究進(jìn)展,為黃芩苷的臨床應(yīng)用提供支持。
[Key word]
[Abstract]
Cerebral hemorrhage is the main cause of death and disability worldwide, with a complex pathogenesis. Baicalin is the main active ingredient in Scutellariae Radix, and can treat cerebral hemorrhage by reducing neuroinflammatory reactions, alleviating oxidative stress reactions, inhibiting neuronal apoptosis, correcting imbalances of inhibitory amino acid gamma aminobutyric acid system, and protecting the integrity of the blood - brain barrier. This article summarizes the pharmacological research progress of baicalin in treatment of cerebral hemorrhage, providing support for the clinical application of baicalin.
[中圖分類號(hào)]
R285
[基金項(xiàng)目]
重慶市衛(wèi)生健康委醫(yī)學(xué)科研項(xiàng)目(2024WSJK100)