丹參酮是從唇形科植物丹參中提取的脂溶性菲醌化合物，具有多種藥理作用，可通過誘導細胞死亡、抑制腫瘤細胞增殖、阻止腫瘤細胞遷移和侵襲、增加放療和化療敏感性發(fā)揮抗腫瘤作用。闡明了丹參酮抗腫瘤作用的研究進展，以期為丹參酮未來癌癥療法的優(yōu)化和發(fā)展提供依據(jù)。

Tanshinones are a kind of fat-soluble phenanthraquinone compounds extracted from Salviae Miltiorrhizae Radix et Rhizoma, which have many pharmacological activities. Tanshinones exert anti-tumor effects by inducing tumor cell death, inhibiting tumor cell proliferation, preventing tumor cell invasion and metastasis, and increasing the sensitivity of radiotherapy and chemotherapy. This article elaborates on the research progress on the anti-tumor effect of tanshinones, in order to provide a basis for the optimization and development of tanshinones in future cancer therapies.

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首都衛(wèi)生發(fā)展科研專項（2022-1-4041）;中國醫(yī)學科學院醫(yī)學與健康科技創(chuàng)新工程項目（2021-I2M-1-052）