目的 統(tǒng)計寧夏回族自治區(qū)寧安醫(yī)院2021—2024年第二類精神藥品使用情況，分析變化趨勢，促進醫(yī)院第二類精神藥品合理使用。方法 采用回顧性分析收集寧夏回族自治區(qū)寧安醫(yī)院2021—2024年第二類精神藥品的銷售金額和使用量，計算第二類精神藥品的用藥頻度（DDDs），限定日費用（DDC）以藥品的排序比（B/A）。結(jié)果 2021—2024年，醫(yī)院第二類精神藥品銷售金額呈現(xiàn)逐漸增長趨勢，奧沙西泮、扎來普隆、勞拉西泮（1 mg）的銷售金額及排序始終位居前列；第二類精神藥品的DDDs總體呈逐年增長趨勢，右佐匹克隆、艾司唑侖、阿普唑侖始終位于前列，右佐匹克隆（3 mg）、扎來普隆分散片DDDs下降明顯；第二類精神藥品的DDC及排序基本平穩(wěn)，奧沙西泮、扎來普隆、地佐辛注射液DDC較高，排名始終在前3位；酒石酸唑吡坦（5 mg）、佐匹克隆片、苯巴比妥片、地西泮片、氯硝西泮片（0.5 mg）地佐辛注射液的B/A均接近1。結(jié)論 寧夏回族自治區(qū)寧安醫(yī)院第二類精神藥品的使用仍存在不合理現(xiàn)象，繼續(xù)加強第二類精神藥品的管理和監(jiān)督，確?；颊哂盟幇踩⒂行?、經(jīng)濟。

Objective To analyze the usage of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital from 2021 to 2024, analyze the changing trend, and promote the rational use of class Ⅱ psychotropic drugs in the hospital. Methods A retrospective analysis was conducted to collect the sales amount and usage of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital from 2021 to 2024. The frequency of use (DDDs) of class Ⅱ psychotropic drugs was calculated, and the daily cost (DDC) was determined based on the drug ranking ratio (B/A). Results From 2021 to 2024, The sales amount of class Ⅱ psychotropic drugs in hospitals is gradually increasing, with sales amount and ranking of oxazepam, zaleplon, and lorazepam (1 mg) consistently ranking among the top; The DDDs of the class Ⅱ psychotropic drugs have shown an overall increasing trend year by year, with levozopiclone, estazolam, and alprazolam consistently ranking among the top. The DDDs of levozopiclone (3 mg) and zaleplon dispersible tablets have decreased significantly. The DDC and ranking of the class Ⅱ psychotropic drugs are basically stable, with oxalazepam, zaleplon, and dizocin injection having higher DDC and consistently ranking in the top 3. The B/A ratios of zolpidem tartrate (5 mg), zopiclone tablets, phenobarbital tablets, diazepam tablets, clonazepam tablets (0.5 mg), and dizoxin injection are all close to 1. Conclusion There are still unreasonable phenomena in the use of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital. We will continue to strengthen the management and supervision of class Ⅱ psychotropic drugs to ensure the safety, effectiveness, and economy of patient medication.

R971

寧夏回族自治區(qū)重點研發(fā)計劃項目資助（2024BEG02026）