目的 建立丁苯酞氯化鈉注射液合理使用評價(jià)標(biāo)準(zhǔn)，為臨床合理使用丁苯酞氯化鈉注射液提供依據(jù)。方法 以丁苯酞氯化鈉注射液說明書、相關(guān)指南為依據(jù)制定評價(jià)標(biāo)準(zhǔn)，并采用屬性層次模型（AHM）對亳州市人民醫(yī)院2023年1～7月丁苯酞氯化鈉注射液的180份出院病歷進(jìn)行評價(jià)。結(jié)果 180例病歷都未在醫(yī)囑標(biāo)注滴注時(shí)間，療程不適宜31例（17.22%）、超適應(yīng)證22例（12.22%）、用藥頻次不適宜5例（2.78%）、超禁忌證2例（1.1%）和未監(jiān)測肝腎功能5例（2.78%）。等級優(yōu)秀病歷120例（66.67%）、良好病歷32例（17.78%）和合格病歷28例（15.55%）。結(jié)論 亳州市人民醫(yī)院丁苯酞氯化鈉注射液存在不合理問題，需要多部門協(xié)作干預(yù)整治。基于屬性層次模型AHM的藥物合理性評價(jià)操作簡單，對多因素指標(biāo)評價(jià)結(jié)果較好，該方法可廣泛用于其他藥物合理性評價(jià)。

Objective To establish the evaluation standard for the rational use of Butylphthalide and Sodium Chloride Injection, and provide a basis for rational clinical use of Butylphthalide and Sodium Chloride Injection. Methods The evaluation criteria of Butylphthalide and Sodium Chloride Injection were developed based on the instruction manual and relevant guidelines, and the attribute hierarchical model was used to evaluate 180 discharged medical records of Bozhou People's Hospital from January to July 2023 for Butylphthalide and Sodium Chloride Injection. Results None of the 180 medical records were labeled with titration time in the medical prescription, inappropriate course of treatment in 31 cases (17.22%), over-indication in 22 cases (12.22%), inappropriate frequency of medication in 5 cases (2.78%), over-contraindications in 2 cases (1.1%), and failure to monitor hepatic and renal functions in 5 cases (2.78%). Grade excellent medical records 120 cases (66.67%), good medical records 32 cases (17.78%) and qualified medical records 28 cases (15.55%). Conclusion There are many unreasonable problems with Butylphthalide and Sodium Chloride Injection in Bozhou People's Hospital, which require multi-departmental collaborative intervention for remediation. The drug rationality evaluation based on attribute hierarchical model is simple to operate and has better evaluation results for multi-factor indicators, and this method can be widely used for other drug rationality evaluation.

R971