目的 分析藥品帶量采購后對蕪湖市中醫(yī)醫(yī)院質(zhì)子泵抑制劑（PPIs）使用情況的影響，為藥品帶量采購工作的執(zhí)行和醫(yī)院藥事管理提供參考。方法 以2020年11月份為政策執(zhí)行點，分別調(diào)取醫(yī)院信息系統(tǒng)（HIS）藥品帶量采購前（2019年5月—2020年10月）與藥品帶量采購后（2020年11月—2022年4月）PPIs的使用數(shù)據(jù)，按照給藥途徑進行分類，采用藥物經(jīng)濟學(xué)方法回顧性分析藥品供應(yīng)目錄、價格、銷售數(shù)量、金額、用藥頻度（DDDs）、日均費用（DDC）變化情況。結(jié)果 藥品集中帶量采購政策執(zhí)行后，PPIs口服劑型消耗量保持穩(wěn)定，銷售金額下降22.09%，注射劑型消耗量下降45.22%，銷售金額下降61.16%，中選品種用藥頻度大幅度提高，日治療費用大幅度降低。結(jié)論 藥品集中帶量采購后，切實減輕了患者的用藥負擔(dān)，有效的節(jié)省了醫(yī)保資金，促進了臨床的合理用藥。

Objective To analyze the effects of drug purchase with quantity on the use of proton pump inhibitors (PPIs) in Wuhu Hospital of Traditional Chinese Medicine, and to provide reference for the implementation of drug purchase with quantity and hospital pharmaceutical management. Methods Taking November 2020 as the policy implementation point, the use data of PPIs of hospital Information System (HIS) before (May 2019-October 2020) and after (November 2020-April 2022) drug delivery volume were collected and classified according to drug delivery route. Pharmacoeconomic methods were used to retrospectively analyze the changes of drug supply list, price, sales quantity, sum, DDDs and DDC. Results After the implementation of the centralized procurement policy, the consumption of oral dosage forms of PPIs remained stable, with the consumption sum decreasing by 22.09%, the consumption of injection dosage forms by 45.22%, and the consumption sum decreasing by 61.16%. The frequency of drug use of selected varieties was greatly improved, and the daily treatment cost was greatly reduced. Conclusion After the centralized procurement of medicines in quantity, the burden of medication on patients is effectively reduced, medical insurance funds are effectively saved, and rational clinical medication is promoted.

R975

安徽高校自然科學(xué)研究重點項目(KJ2020A0877)