目的 對(duì)"4+7"帶量采購(gòu)5-羥色胺再攝取抑制劑(SSRIs)抗抑郁藥的使用情況進(jìn)行分析,為醫(yī)院藥事管理提供參考。方法 調(diào)取烏魯木齊市第四人民醫(yī)院信息系統(tǒng)(HIS)中帶量采購(gòu)實(shí)施后1年(2019年11月20日-2020年11月20日)和實(shí)施前1年(2018年11月19日-2019年11月19日)醫(yī)院SSRI類抗抑郁藥的使用數(shù)量、銷售金額、用藥頻度(DDDs)、日均費(fèi)用(DDC)等進(jìn)行分析。結(jié)果 "4+7"帶量采購(gòu)政策實(shí)施后,帕羅西汀的銷售金額顯著下降,艾司西酞普蘭使用片數(shù)有所增長(zhǎng)。帕羅西汀的DDDs值與去年持平,艾司西酞普蘭的DDDs值有小幅的增長(zhǎng)。帕羅西汀與艾司西酞普蘭的DDC值與去年同期相比均有明顯下降。結(jié)論 "4+7"采購(gòu)政策實(shí)施后,烏魯木齊市第四人民抑郁癥患者的用藥負(fù)擔(dān)顯著下降。

Objective To analyze the use of SSRIs antidepressants in implementation of “4＋7” procurement with quantity, and to provide reference for hospital pharmacy management. Methods Quantity, consumption sum, DDDs, and DDC of SSRI antidepressants after implementation (November 20, 2019 — November 20, 2020) and implementation (November 19, 2018 — November 19, 2019) were collected from the information system of Urumqi No. 4 People's Hospital for analysis. Results After the implementation of “4＋7” procurement with quantity, consumption sum of paroxetine dropped significantly, and the usage quantity of escitalopram was increased, DDDs of paroxetine were the same as last year, DDDs of escitalopram increased slightly. DDC values of paroxetine and escitalopram decreased significantly compared with the same period last year. Conclusion After implementation of “4＋7” procurement with quantity, the medication burden of patients with depression showed a significant decrease.

R971