目的 調(diào)查分析2018—2020年天津市津南醫(yī)院抗腦血管病藥的應(yīng)用情況及趨勢(shì)，為醫(yī)院抗腦血管病藥的科學(xué)管理和合理應(yīng)用提供參考。方法 采用數(shù)據(jù)回顧性方法，對(duì)天津市津南醫(yī)院抗腦血管病藥的用藥總金額、用藥總數(shù)量及構(gòu)成比、限定日計(jì)量（DDD）值、用藥頻度（DDDs）及日均費(fèi)用（DDC）等數(shù)據(jù)進(jìn)行統(tǒng)計(jì)與分析。結(jié)果 天津市津南醫(yī)院共有24種抗腦血管病藥，抗腦血管病藥的銷售金額逐年下降。2018—2019年，口服抗腦血管病藥中口服水解蛋白、胞磷膽堿鈉片和長(zhǎng)春西汀片（5 mg）的銷售金額排名始終排名前3位，且2020年胞磷膽堿鈉片的銷售金額排名居首位。注射用抗腦血管病藥中除2019年的銀杏葉提取物注射液，丁苯酞氯化鈉注射液、奧拉西坦注射液、銀杏葉提取物注射液的銷售金額排名始終居前3位。口服抗腦血管病藥中除了2020年的奧拉西坦膠囊，奧拉西坦膠囊、鹽酸氟桂利嗪膠囊、胞磷膽堿鈉片的DDDs排名始終居前3位。注射用抗腦血管病藥中除了2020年的注射用七葉皂苷鈉（10 mg）和2019年的銀杏葉提取物注射液，其他時(shí)間二者的DDDs排名均在前2位。2018—2020年，除了口服水解蛋白DDC值高于50元外，其他口服抗腦血管病藥的DDC均低于10元。2018—2020年，除了丁苯酞氯化鈉注射液和注射用奧拉西坦DDC值高于200元，其他類注射用抗腦血管病藥的DDC值均低于200元。結(jié)論 天津市津南醫(yī)院抗腦血管病藥的管理比較規(guī)范，藥物使用大致合理。

Objective To investigate and analyze the application and trend of anti-cerebrovascular disease drugs in Tianjin Jinnan Hospital from 2018 to 2020, so as to provide references for the scientific management and rational application of anti-cerebrovascular disease drugs in Tianjin Jinnan Hospital.Methods Data retrospective method was used to calculate the total amount of anti-cerebrovascular disease drugs used in Tianjin Jinnan Hospital. The total consumption sum, total quantity and composition ratio, DDD value, DDDs and DDC of anti-cerebrovascular drugs in Tianjin Jinnan Hospital were analyzed statistically.Results There are 24 kinds of anti-cerebrovascular disease drugs in Tianjin Jinnan Hospital. The sales amounts of anti-cerebrovascular disease drugs were decreasing year by year. From 2018 to 2019, the sales amounts of Oral Protein Hydrolysate, Citicoline Sodium Tablets, and Vinpocetine Tablets (5 mg) always ranked the top 3, and the consumption sum of Citicoline Sodium Tablets ranked the first in 2020. In addition to Extract of Ginkgo Biloba Leaves Injection in 2019, the sales value of Butylphthalide and Sodium Chloride Injection, Oxiracetam Injection, and Extract of Ginkgo Biloba Leaves Injection always ranked the top 3. In addition to the DDDs of Oxiracetam Capsules in 2020, the DDDs of Oxiracetam Capsules, Flunarizine Hydrochloride Capsules, and Citicoline Sodium Tablets always ranked the top 3. Except for Sodium Aescinate for injection (10 mg) in 2020 and Extract of Ginkgo Biloba Leaves Injection in 2019, the DDDs of both of them ranked top 2 in other times. From 2018 to 2020, DDC values of other oral anti-cerebrovascular drugs were all less than 10 yuan, except DDC values of Oral Protein Hydrolysate were higher than 50 yuan. From 2018 to 2020, the DDC values of other anti-cerebrovascular diseases drugs for injection were all lower than 200 yuan, except that the DDC values of Butylphthalide and Sodium Chloride Injection and Oxiracetam for Injection were higher than 200 yuan.Conclusion The management of anti-cerebral vascular drugs in Tianjin Jinnan Hospital is relatively standardized, and the use of drugs is generally reasonable.

R971

國家自然科學(xué)基金青年項(xiàng)目（8180130669）