目的 探討新血寶膠囊聯(lián)合二維亞鐵顆粒治療缺鐵性貧血的臨床療效。方法 選取2019年5月—2021年5月天津醫(yī)科大學(xué)總醫(yī)院收治的200例缺鐵性貧血患者，按照隨機(jī)數(shù)字表法分為對照組和治療組，每組各100例。對照組口服二維亞鐵顆粒，5 g/次，2次/d。治療組在對照組基礎(chǔ)上口服新血寶膠囊，2粒/次，3次/d。所有患者采用上述治療方案連續(xù)治療4周。觀察兩組的臨床療效，比較兩組臨床癥狀改善時間、血常規(guī)指標(biāo)和鐵代謝指標(biāo)。結(jié)果 治療后，治療組總有效率是98%，顯著高于對照組的88%（P<0.05）。治療過程中，治療組乏力、頭暈、心悸、面色蒼白好轉(zhuǎn)時間均顯著短于對照組（P<0.05）。治療后，兩組血紅蛋白（HGB）、紅細(xì)胞計數(shù)（RBC）、平均紅細(xì)胞體積（MCV）、網(wǎng)織紅細(xì)胞計數(shù)（RET）水平均較治療前顯著增高（P<0.05），治療后治療組血常規(guī)指標(biāo)顯著高于對照組（P<0.05）。治療后，兩組血清鐵（SI）、血清鐵蛋白（SF）水平均較治療前顯著提高，但總鐵結(jié)合力（TIBC）水平顯著降低（P<0.05）；治療后，治療組患者鐵代謝指標(biāo)改善優(yōu)于對照組（P<0.05）。治療后，兩組生活滿意度評分均顯著升高（P<0.05），且治療后治療組生活滿意度評分高于對照組（P<0.05）。結(jié)論 新血寶膠囊聯(lián)合二維亞鐵顆粒治療缺鐵性貧血具有較好的臨床療效，可有效改善患者貧血癥狀，改善血常規(guī)指標(biāo)和鐵代謝指標(biāo)，提高患者生活滿意度，值得臨床借鑒與推廣使用。

Objective To investigate the clinical efficacy of Xinxuebao Capsules combined with two-dimensional ferrous in treatment of iron deficiency anemia. Methods A total of 200 patients with iron deficiency anemia admitted to General Hospital of Tianjin Medical University from May 2019 to May 2021 were selected and divided into control group and treatment group according to random number table method, with 100 cases in each group. Patients in the control group were po administered with Compound Ferrous Fumarate and Vitamin B Granules, 5 g/time, twice daily. Patients in the treatment group were po administered with Xinxuebao Capsules on the basis of the control group, 2 grains/times, three times daily. All patients were treated with the above treatment regimen for 4 weeks. The clinical efficacy of the two groups were observed, and the improvement time of clinical symptoms, blood routine indexes and iron metabolism indexes were compared between the two groups. Results After treatment, the total effective rate of the treatment group was 98%, significantly higher than that of the control group (88%) (P<0.05). During the treatment, the improvement time of fatigue, dizziness, palpitation, and pallor in the treatment group was significantly shorter than that in the control group (P<0.05). After treatment, the levels of hemoglobin (HGB), red blood cell count (RBC), mean red blood cell volume (MCV) and reticulocyte count (RET) in two groups were significantly higher than those before treatment (P<0.05), and blood routine indexes in treatment group were significantly higher than those in control group (P<0.05). After treatment, the levels of serum iron (SI) and serum ferritin (SF) in two groups were significantly increased compared with before treatment, but the level of total iron binding ability (TIBC) was significantly decreased (P<0.05). After treatment, the improvement of iron metabolism index in the treatment group was better than that in the control group (P<0.05). After treatment, the life satisfaction scores of the two groups were significantly increased (P<0.05), and the life satisfaction scores of the treatment group were higher than that of the control group (P<0.05). Conclusion Xinxuebao Capsules combined with Compound Ferrous Fumarate and Vitamin B Granules has good clinical efficacy in treatment of iron deficiency anemia, and can effectively improve anemia symptoms, and can improve blood routine indexes and iron metabolism indexes, and improve life satisfaction, which is worthy of reference and promotion.

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