目的 分析2017-2019年天津市濱海新區(qū)漢沽中醫(yī)醫(yī)院Ⅰ類(lèi)切口圍手術(shù)期抗菌藥物預(yù)防使用情況，為規(guī)范Ⅰ類(lèi)切口圍手術(shù)期抗菌藥物預(yù)防使用提供參考。方法 抽取天津市濱海新區(qū)漢沽中醫(yī)醫(yī)院2017-2019年Ⅰ類(lèi)切口手術(shù)病歷共163例，對(duì)圍手術(shù)期預(yù)防用抗菌藥物情況及合理性進(jìn)行評(píng)價(jià)與分析。結(jié)果 163例患者中48例預(yù)防使用了抗菌藥物，抗菌藥物使用率為29.45%；抗菌藥物品種選擇排名第一的為頭孢西丁，構(gòu)成比為50%，頭孢唑林、頭孢替唑、氨曲南以及美洛西林舒巴坦，構(gòu)成比均為12.50%；給藥時(shí)機(jī)在術(shù)前0.5~1 h給藥的有30例，占62.5%；用藥療程≤ 24 h的有30例，占62.5%；用法用量不適宜的有23例，其中頭孢西丁17例、氨曲南6例。結(jié)論 天津市濱海新區(qū)漢沽中醫(yī)醫(yī)院Ⅰ類(lèi)切口圍手術(shù)期預(yù)防用抗菌藥物存在用藥指征把握不嚴(yán)、品種選擇不恰當(dāng)、給藥時(shí)機(jī)不恰當(dāng)、用藥療程過(guò)長(zhǎng)、用法用量不合理等問(wèn)題，應(yīng)加強(qiáng)管理，促進(jìn)Ⅰ類(lèi)切口圍手術(shù)期抗菌藥物合理應(yīng)用。

Objective To analyze the usage of prophylactic antibiotiscs in perioperative period of type Ⅰ incision in Hangu Hospital of Traditional Chinese Medicine in Tianjin Binhai New Area from 2017 to 2019, and so as to provide reference for the prophylactic application of antibiotiscs in perioperative period of type Ⅰ incision. Methods A total of 163 medical records undergoing type Ⅰ incision operation in Hangu Hospital of Traditional Chinese Medicine in Tianjin Binhai New Area from 2017 to 2019 were randomly selected, and the usage of prophylactic antibiotics in perioperative period and rationality were evaluated and analyzed. Results In the 163 cases of patients, there were 48 cases of patients with prophylactic antibiotiscs, and the usage rate of antibiotics was 29.45%. In the ranking of selecting the types of antibiotiscs, the first one was cefoxitin, accounting for 50%. Cefazolin, ceftizole, aztreonam, mezlocillin and sulbactam all accounted for 12.50%. The cases of administration time 0.5-1 h before operation was 30, accounting for 62.5%. The proportion of patients with drug course within 24 h was 62.5%. The cases of unreasonableusage and dosage was 23, 17 cases were the applications of cefoxitin, and 6 cases were the applications of aztreonam. Conclusion There are unreasonable phenomenon of antibiotics use in type Ⅰ incision operation in Hangu Hospital of Traditional Chinese Medicinein Tianjin Binhai New Area, especially including improper medication indications, incorrect choice of drugs, inappropriate timing of administration, long duration, unreasonableusage and dosage. It is necessary to strengthen the management of antibiotiscs, and so as to promote the rational use of antibiotics in clinic.

R978.1