目的 探討橘紅痰咳液聯(lián)合莫西沙星注射液治療痰濁阻肺型老年社區(qū)獲得性肺炎的臨床效果。方法 選取2018年11月-2019年2月天津中醫(yī)藥大學(xué)第一附屬醫(yī)院收治的120例老年痰濁阻肺型社區(qū)獲得性肺炎患者，將所有患者隨機分為對照組和治療組，每組各60例。對照組靜脈滴注鹽酸莫西沙星氯化鈉注射液，250 mL/次，1次/d。治療組患者在對照組治療基礎(chǔ)上口服橘紅痰咳液，20 mL/次，3次/d，兩組均連續(xù)治療7 d。觀察兩組的臨床療效和影像學(xué)吸收情況，比較兩組臨床癥狀緩解時間和治療前后白細(xì)胞計數(shù)（WBC）、C反應(yīng)蛋白（CRP）、降鈣素原（PCT）的變化。結(jié)果 治療后，治療組總有效率為95.00%，顯著高于對照組的88.33%（P<0.05）。治療組患者體溫恢復(fù)正常、咳嗽消失時間均顯著短于對照組（P<0.05）。治療后，兩組患者WBC、CRP、PCT水平較治療前明顯降低（P<0.05）；且治療后，治療組這些炎癥指標(biāo)比較降低更顯著（P<0.05）。治療后，對照組影像學(xué)總吸收率是98.33%，治療組是96.66%，兩組比較差異無統(tǒng)計學(xué)意義。結(jié)論 橘紅痰咳液聯(lián)合莫西沙星注射液治療痰濕阻肺型老年社區(qū)獲得性肺炎患者具有較好的臨床療效，可縮短癥狀緩解時間，減輕炎癥反應(yīng)程度，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the clinical effect of Juhong Tanke Liquid combined with moxifloxacin in treatment of community-acquired pneumonia of the elderly with turbid phlegm obstructing lung. Methods 120 Patients with community-acquired pneumonia of the elderly with turbid phlegm obstructing lung who were treated in the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from November 2018 to February 2019 were selected as the research objects, and they were randomly divided into control group (60 cases) and treatment group (60 cases). Patients in the control group were iv administered with Moxifloxacin Hydrochloride and Sodium Chloride Injection, 250 mL/time, once daily. Patients in the treatment group were po administered with Juhong Tanke Liquid on the basis of the control group, 20 mL/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy and imaging absorption of the two groups were observed, and the changes of white blood cell count (WBC), C-reactive protein (CRP) and procalcitonin (PCT) before and after treatment were compared between the two groups. Results After treatment, the total effective rate of the treatment group 95.00% was significantly higher than that of the control group (88.33%, P<0.05). After treatment, the temperature returned to normal and cough disappeared time in the treatment group was significantly shorter than that in the control group (P<0.05). After treatment, WBC, CRP, and PCT levels in the two groups were significantly lower than before treatment (P<0.05). After treatment, the reduction of these inflammatory indicators in the treatment group was more significant (P<0.05). After treatment, the total imaging absorption rate was 98.33% in the control group and 96.66% in the treatment group, and there was no statistically significant difference between the two groups. Conclusion Juhong Tanke Liquid combined with moxifloxacin has good clinical effect in treatment of community-acquired pneumonia of the elderly with turbid phlegm obstructing lung, and can shorten the remission of symptoms, and also can reduce the inflammation degree, which has certain clinical application value.

R974

天津中醫(yī)藥大學(xué)第一附屬醫(yī)院“拓新工程”科研課題（201909）