目的 分析天津中醫(yī)藥大學第一附屬醫(yī)院胰島素類藥物的使用情況和變化趨勢，為促進臨床合理用藥提供參考。方法 通過醫(yī)院信息系統(tǒng)（HIS）提取2017-2019年天津中醫(yī)藥大學第一附屬醫(yī)院胰島素類藥物的銷售金額、使用頻度（DDDs）、日均費用（DDC）和排序比（B/A）等進行統(tǒng)計和分析。結果 2017-2019年共有11種胰島素類藥物供臨床使用，銷售金額和構成比呈先下降后上升的趨勢。甘精胰島素注射液的銷售金額及構成比連續(xù)3年居第1位，門冬胰島素30注射液次之。胰島素類各品種的金額和DDDs排序無顯著波動，排名基本穩(wěn)定，只有地特胰島素的上升幅度較大。除胰島素注射液和地特胰島素注射液外，其余品種的DDC值均逐年小幅下降。除門冬胰島素30注射液外，其余品種的B/A比值均接近1.00。結論 天津中醫(yī)藥大學第一附屬醫(yī)院胰島素類藥物的選擇和使用基本合理，個別增長速度過快品種需密切關注，確保臨床用藥規(guī)范合理。

Objective To analyze the utilization and tendency of insulin drugs in First Teaching Hospital of Tianjin University of TCM, and in order to provide reference and management for clinical rational use of drugs. Methods The relevant data of utilization of insulin drugs in First Teaching Hospital of Tianjin University of TCM from 2017 to 2019 was selected from Hospital Information Systems (HIS), and drug varieties, sales amount, defined daily doses (DDDs), defined daily cost (DDC), and sorting ratio (B/A) were analyzed statistically. Results From 2017 to 2019, there were 11 insulin kinds for clinical use, and the sales amount and composition ratio showed a downward trend first and then upward trend. The sales amount and composition ratio of Insulin Glargine Injection ranked the first for three consecutive years, followed by insulin Aspart 30 Injection. There was no significant fluctuation in the amount and DDDs of insulin varieties. The ranking was basically stable, but the rising range of Insulin Detemir Injection was large. In addition to Insulin Injection and Insulin Detemir Injection, DDC of other varieties decreased slightly year by year. The B/A of the other varieties was close to 1.00 except for Insulin Aspart 30 Injection.Conclusion The selection and use of insulin drugs in the First Teaching Hospital of Tianjin University of TCM are basically reasonable, and the individual varieties with excessive growth rate need to be paid more attention to ensure that the use of drugs is standardized and reasonable.

R977