目的 了解華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院腫瘤中心麻醉性鎮(zhèn)痛藥品的用藥情況及用藥趨勢，為臨床合理用藥提供依據(jù)。方法 對2015-2017年華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院腫瘤中心麻醉性鎮(zhèn)痛藥品的用藥品種、銷售金額、用藥頻度（DDDs）、日均藥費(fèi)（DDC）和排序比（B/A）進(jìn)行統(tǒng)計分析。結(jié)果 2015-2017年，麻醉性鎮(zhèn)痛藥品的銷售金額逐年增加。芬太尼透皮貼劑的用量逐年下降，鹽酸羥考酮緩釋片的用量逐年上升，鹽酸嗎啡注射液、鹽酸哌替啶注射液和鹽酸布桂嗪注射液3種注射液的用量略有浮動，但總體用量都較少。兩種規(guī)格鹽酸羥考酮緩釋片的銷售金額一直位于第1、2位，兩種規(guī)格芬太尼透皮貼劑的銷售金額一直處于第3、4位。鹽酸羥考酮緩釋片、芬太尼透皮貼劑和硫酸嗎啡緩釋片的DDC值偏高，且B/A值小于或等于1.00，其他麻醉藥品的DDC值均較小。結(jié)論 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院腫瘤中心麻醉性鎮(zhèn)痛醉藥品的使用情況與《麻醉藥品臨床應(yīng)用指導(dǎo)原則》所規(guī)定的基本相符合，但仍有必要對癌痛的規(guī)范化治療進(jìn)行培訓(xùn)，加強(qiáng)對"三階梯治療"相關(guān)知識的認(rèn)識和理解。

Objective To investigate the use of narcotic analgesic drugs in Tumor Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, and to provide reference for reasonable application of narcotic analgesic drugs. Methods Statistical analysis was conducted on drug category, consumption sums, defined daily dose system (DDDs), average daily cost (DDC), and B/A values of narcotic analgesic drugs in Tumor Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology from 2015 to 2017. Results From 2015 to 2017, consumption sums of narcotic analgesic drugs were increased year by year. Amounts of Fentanyl Transdermal Patches were decreased year by year, while amounts of Oxycodone Hydrochloride Prolonged-release Tablets were increased year by year. Amounts of Morphine Hydrochloride Injection, Pethidine Hydrochloride Injection, and Bucinnazine Hydrochloride Injection were slightly floated, and their amounts were less. Consumption sums of Oxycodone Hydrochloride Prolonged-release Tablets with two specifications were ranked the first and second. Consumption sums of Fentanyl Transdermal Patches with two specifications were ranked the third and fourth. DDC of Oxycodone Hydrochloride Prolonged-release Tablets, Fentanyl Transdermal Patches, and Morphine Sulfate Sustained-release Tablets were high, and the B/A values of them were much less than or equal to 1.00. DDC of other narcotic drugs were all small. Conclusion The use of narcotic analgesic drugs in Tumor Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology is basically consistent with that stipulated in the Guiding Principles of Clinical Application of Narcotic Drugs. However, there is still a need to step up the standardization of cancer pain treatment, and to enhance understanding of the relevant knowledge of the "three-tiered cancer pain ladder".