目的 探討百合固金顆粒聯(lián)合左氧氟沙星治療社區(qū)獲得性肺炎的臨床療效。方法 選取2016年1月-2016年12月在陜西省第四人民醫(yī)院進(jìn)行治療的社區(qū)獲得性肺炎患者78例，隨機(jī)分為對(duì)照組（39例）和治療組（39例）。對(duì)照組靜脈滴注乳酸左氧氟沙星氯化鈉注射液，0.5 g/次，1次/d；治療組在對(duì)照組基礎(chǔ)上口服百合固金顆粒，9 g/次，2次/d。兩組患者均治療7 d。評(píng)價(jià)兩組患者臨床療效，同時(shí)比較治療前后兩組患者臨床癥狀改善時(shí)間和血清學(xué)指標(biāo)。結(jié)果 治療后，對(duì)照組和治療組臨床有效率分別為79.49%和94.87%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組患者發(fā)熱、咳痰、胸痛、氣促、肺部啰音、胸片炎癥吸收改善時(shí)間均明顯短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者血清超敏C反應(yīng)蛋白（hs-CRP）、降鈣素（PCT）、白細(xì)胞計(jì)數(shù)（WBC）、中性粒細(xì)胞比例（NEU）水平均顯著降低，同組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組上述血清學(xué)指標(biāo)明顯低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 采用百合固金顆粒聯(lián)合左氧氟沙星治療社區(qū)獲得性肺炎患者不僅可以改善臨床癥狀，還可降低機(jī)體炎癥反應(yīng)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical efficacy of Baihe Gujin Granules combined with levofloxacin in treatment of community-acquired pneumonia. Methods Patients (78 cases) with community-acquired pneumonia in the Fourth People's Hospital of Shaanxi from January 2016 to December 2016 were randomly divided into control (39 cases) and treatment (39 cases) groups. Patients in the control group were iv administered with Levofloxacin Lactate and Sodium Chloride Injection, 0.5 g/time, once daily. Patients in the treatment group were po administered with Baihe Gujin Granules on the basis of the control group, 9 g/time, twice daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the improvement time of clinical symptoms, the serological indexes in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 79.49% and 94.87% respectively, and there were differences between two groups (P<0.05). After treatment, the improvement time of fever, expectoration, pectoralgia, anhelation, lung rale and inflammatory absorption of the chest in the treatment group after treatment was significantly shorter than those in the control group, with significant difference between two groups (P<0.05). After treatment, the hs-CRP, PCT, WBC and NEU levels in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the serological indexes levels in the treatment group after treatment were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Baihe Gujin Granules combined with levofloxacin in treatment of community-acquired pneumonia can improve the clinical symptoms and reduce inflammation, which has a certain clinical application value.