目的 探討芪參益氣滴丸聯(lián)合米力農(nóng)注射液治療擴(kuò)張性心肌病心力衰竭的臨床療效。方法 選取2014年5月-2017年5月天津市第三中心醫(yī)院分院心內(nèi)科收治的擴(kuò)張性心肌病心力衰竭患者64例為研究對(duì)象，將所有患者隨機(jī)分為對(duì)照組和治療組，每組各32例。對(duì)照組靜脈泵注米力農(nóng)注射液，0.3 μg/（kg·min），10 mg/d；治療組在對(duì)照組的基礎(chǔ)上口服芪參益氣滴丸，1袋/次，3次/d。兩組均連續(xù)治療10 d。觀察兩組的臨床療效，比較兩組的心功能指標(biāo)和生化指標(biāo)。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為75.0%、93.8%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組心排出量（CO）、每搏輸出量（SV）、左室射血分?jǐn)?shù)（LVEF）均顯著升高，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些心功能指標(biāo)明顯高于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組肌鈣蛋白I（cTnI）和腦利鈉肽（BNP）水平均顯著降低，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些生化指標(biāo)明顯低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 芪參益氣滴丸聯(lián)合米力農(nóng)注射液治療擴(kuò)張性心肌病心力衰竭具有較好的臨床療效，能改善心功能，降低cTnI、BNP水平，安全性較好，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical efficacy of Qishen Yiqi Dripping Pills combined with Milrinone Injection in treatment of dilated cardiomyopathy with heart failure. Methods Patients (64 cases) with dilated cardiomyopathy with heart failure in Branch of Tianjin Third Hospital from May 2014 to May 2017 were randomly divided into control and treatment groups, and each group had 32 cases. Patients in the control group were intravenous pump injection administered with Milrinone Injection, 0.3 μg/(kg·min), 10 mg/d. Patients in the treatment group were po administered with Qishen Yiqi Dripping Pills on the basis of the control group, 1 bag/time, three times daily. Patients in two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and cardiac function indexes and biochemical indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.0% and 93.8%, respectively, and there was difference between two groups (P < 0.05). After treatment, CO, LVEF, and SV in two groups were significantly increased, and the difference was statistically significant in the same group (P < 0.05). And the cardiac function indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the levels of cTnI and BNP in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the biochemical indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Qishen Yiqi Dripping Pills combined with Milrinone Injection has clinical curative effect in treatment of dilated cardiomyopathy with heart failure, can improve cardiac function, and decrease the levels of cTnI and BNP, with good safety, which has a certain clinical application value.