目的 探究消痔靈注射液聯(lián)合地奧司明片治療內(nèi)痔的臨床療效。方法 選取2014年1月—2016年5月上海市第一人民醫(yī)院寶山分院收治的內(nèi)痔患者96例作為研究對(duì)象，按隨機(jī)數(shù)字表法將所有患者分為對(duì)照組和治療組，每組各48例。對(duì)照組口服地奧司明片，3片/次，2次/d。治療組在對(duì)照組治療的基礎(chǔ)上內(nèi)痔局部注射消痔靈注射液，根據(jù)內(nèi)痔大小，每個(gè)痔核注藥3~5 mL。兩組患者均連續(xù)治療7 d。觀察兩組的臨床療效，比較兩組的臨床癥狀評(píng)分。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為75.00%、93.75%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P < 0.05）。治療后，兩組便血、疼痛、墜脹、水腫、瘙癢評(píng)分和總分均顯著降低，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P < 0.05）；且治療組這些觀察指標(biāo)明顯低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P < 0.05）。結(jié)論 消痔靈注射液聯(lián)合地奧司明片治療內(nèi)痔具有較好的臨床療效，能夠改善臨床癥狀，安全性較好，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical efficacy of Xiaozhiling Injection combined with Diosmin Tablets in treatment of hemorrhoids. Methods Patients (96 cases) with hemorrhoids in Baoshan Branch of Shanghai First People's Hospital from January 2014 to May 2016 were randomly divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Diosmin Tables, 3 tablets/time, twice daily. Patients in the treatment group were local injection administered with Xiaozhiling Injection around hemorrhoids on the basis of the control group, according to the internal size of each hemorrhoids injection 3 — 5 mL. Patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, and the clinical symptom score in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.00% and 93.75%, respectively, and there was difference between two groups (P < 0.05). After treatment, hematochezia scores, pain scores, distension scores, edema scores, itching scores, and total scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Xiaozhiling Injection combined with Diosmin Tablets has clinical curative effect in treatment of hemorrhoids, can improve clinical symptoms, with good safety, which has a certain clinical application value.