目的 對西安交通大學(xué)第一附屬醫(yī)院麻醉性鎮(zhèn)痛藥的臨床應(yīng)用情況及用藥趨勢進(jìn)行分析，為麻醉性鎮(zhèn)痛藥的規(guī)范化管理和臨床合理用藥提供參考。方法 采用回顧性分析方法，調(diào)取西安交通大學(xué)第一附屬醫(yī)院2013-2016年麻醉性鎮(zhèn)痛藥的用藥數(shù)據(jù)，對用藥總量、銷售金額、用藥頻度（DDDs）、限定日費(fèi)用（DDC）和排序比（B/A）等進(jìn)行統(tǒng)計分析。結(jié)果 麻醉性鎮(zhèn)痛藥的總銷售金額呈逐年遞增趨勢。枸櫞酸芬太尼注射液、注射用鹽酸瑞芬太尼與芬太尼透皮貼劑在各年度DDDs均居于前幾位。2013-2016年各藥品的DDC值基本穩(wěn)定不變，緩釋劑型的DDC普遍高于普通劑型。鹽酸羥考酮緩釋片（10 mg）和注射用鹽酸瑞芬太尼的B/A較小，而枸櫞酸芬太尼注射液（0.1 mg）的B/A偏高。結(jié)論 西安交通大學(xué)第一附屬醫(yī)院麻醉性鎮(zhèn)痛藥應(yīng)用基本合理，基本符合《癌癥三階梯止痛指導(dǎo)原則》。

Objective To analyze the application and tendency of narcotic analgesic drugs in the First Affiliated Hospital of Xi'an Jiaotong University, so as to provide reference for standard management and clinical rational use of drugs. Methods A retrospective study was conducted. The data of utilization of narcotic analgesic drugs in the First Affiliated Hospital of Xi'an Jiaotong University from 2013 to 2016 were collected and analyzed statistically, and amounts, consumption sums, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and analyzed. Results Total consumption sums of narcotic analgesic drugs increased year by year. DDDs of Fentanyl Citrate Injection, Remifentanil Hydrochloride for Injection, and Fentanyl Transdermal Patches in every year ranked the forefront. DDC of narcotic analgesic drugs was basically stable from 2013 to 2016. DDC of slow release formulation was higher than ordinary dosage forms. B/A of Oxycodone Hydrochloride Prolonged-release Tablets (10 mg) and Remifentanil Hydrochloride for injection were low, but B/A of Fentanyl Citrate Injection (0.1 mg) was high. Conclusion The utilization of narcotic analgesic drugs is rational in the First Affiliated Hospital of Xi'an Jiaotong University on the whole, which is in line with the "Three Ladder Analgesic Treatment Programs of Cancer Pain".