目的 探討雙歧桿菌三聯(lián)活菌散聯(lián)合醒脾養(yǎng)兒顆粒治療嬰幼兒肺炎繼發(fā)性腹瀉的臨床療效。方法 選取淮安市淮安醫(yī)院2015年1月-2017年1月收治的嬰幼兒肺炎繼發(fā)性腹瀉患兒108例，隨機(jī)分成對(duì)照組（54例）與治療組（54例）。對(duì)照組患兒口服醒脾養(yǎng)兒顆粒，0~1歲1 g/次，2次/d； 1~2歲2 g/次，2次/d； 2~3歲4 g/次，2次/d。治療組在對(duì)照組基礎(chǔ)上口服雙歧桿菌三聯(lián)活菌散，0~1歲0.5 g/次，3次/d； 1~3歲1 g/次，3次/d。兩組患兒均連續(xù)治療7 d。評(píng)價(jià)兩組患兒臨床療效，同時(shí)比較治療前后兩組患兒癥狀體征消失時(shí)間和大便次數(shù)。結(jié)果 治療后，對(duì)照組患兒總有效率為75.93%，顯著低于治療組的90.74%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療組循環(huán)不良、嘔吐和腹瀉消失時(shí)間比對(duì)照組顯著縮短，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。在第3、5、7天治療組大便次數(shù)顯著少于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 雙歧桿菌三聯(lián)活菌散聯(lián)合醒脾養(yǎng)兒顆粒治療嬰幼兒肺炎繼發(fā)性腹瀉可有效緩解臨床癥狀體征、提高臨床療效，且安全性高，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical effect of Bifid Triple Viable Powder combined with Xingpi Yanger Granules in treatment of secondary diarrhea of infantile pneumonia. Methods Children (108 cases) with secondary diarrhea of pneumonia in Huaian Hospital of Huaian from January 2015 to January 2017 were randomly divided into control (54 cases) and treatment (54 cases) groups. Children in the control group were po administered with Xingpi Yanger Granules, 1 g/time for 0-1 year old children, 2 g/time for 1-2 year old children, 4 g/time for 2-3 year old children, twice daily. Children in the treatment group were po administered with Bifid Triple Viable Powder on the basis of the control group, 0.5 g/time for 0-1 year old children, 1 g/time for 1-3 year old children, three times daily. Children in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the disappearance time of symptoms and signs, and the frequency of stools in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 75.93%, which was significantly lower than 90.74% in the treatment group, and the difference was statistically significant between two groups (P<0.05). After treatment, the disappearance time of poor circulation, vomit and diarrhea in the treatment group was shorter than that in the control group, with significant difference between two groups (P<0.05). After treatment for 2, 4, and 6 d, the frequency of stools in the treatment group was significantly less than that in the control group, with significant difference between two groups (P<0.05). Conclusion Bifid Triple Viable Powder combined with Xingpi Yanger Granules can effectively alleviate the clinical symptoms and improve clinical efficacy in treatment of secondary diarrhea of infantile pneumonia with high safety, which has a certain clinical application value.