目的 觀察丹紅注射液聯(lián)合氟桂利嗪治療椎基底動脈供血不足眩暈的臨床療效。方法 選取2016年2月-2017年2月在黃石市中心醫(yī)院就診的椎基底動脈供血不足眩暈患者96例，隨機分為對照組和治療組，每組各48例。對照組患者睡前口服鹽酸氟桂利嗪膠囊，5 mg/次，1次/d；治療組在對照組的基礎(chǔ)上靜脈滴注丹紅注射液，30 mL加入5%葡萄糖注射250 mL中，1次/d。兩組患者均治療14 d。評價兩組患者臨床療效，同時比較治療前后兩組患者三酰甘油（TG）、膽固醇（TC）、高切全血黏度、低切全血黏度、椎基底動脈最大血流速度和臨床癥狀改善情況。結(jié)果 治療后，對照組和治療組的總有效率分別為83.33%、91.67%，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，兩組TG、TC、高切全血黏度和低切全血黏度指標水平均顯著下降（P<0.05）；且治療組患者上述指標明顯低于對照組（P<0.05）。治療后，兩組患者椎基底動脈最大血流速度均明顯增加（P<0.05）；且治療組患者椎基底動脈最大血流速度明顯高于對照組（P<0.05）。治療后，兩組患者眩暈積分均明顯改善（P<0.05）；且治療組患者眩暈積分明顯低于對照組（P<0.05）。結(jié)論 丹紅注射液聯(lián)合氟桂利嗪治療椎基底動脈供血不足性眩暈臨床療效確切，不良反應(yīng)較輕，具有一定的臨床推廣應(yīng)用價值。

Objective To observe the clinical curative effect of Danhong Injection combined with flunarizine in treatment of vertebrobasilar insufficiency vertigo. Methods Patients (96 cases) with vertebrobasilar insufficiency vertigo in Huangshi Central Hospital from February 2016 to February 2017 were randomly divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Flunarizine Hydrochloride Capsules, 5 mg/time, once daily. Patients in the treatment group were iv administered with Danhong Injection on the basis of the control group, 30 mL added into 5% glucose injection 250 mL, once daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and the improvement of TG, TC, high blood viscosity, low shear blood viscosity, maximum blood flow velocity of vertebrobasilar artery and clinical symptoms in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 91.67%, respectively, and there was difference between two groups (P<0.05). After treatment, the TG, TC, high blood viscosity, and low shear blood viscosity in two groups were significantly decreased (P<0.05). And these indexes in the treatment group were obviously better than those in the control group (P<0.05). After treatment, the maximum blood flow velocity of vertebrobasilar artery in two groups were significantly increased (P<0.05). And the velocity in the treatment group was obviously higher than that in the control group (P<0.05). After treatment, the vertigo symptom score in two groups were significantly improved (P<0.05). And the vertigo symptom score in the treatment group was significantly lower than that in the control group (P<0.05). Conclusion Danhong Injection combined with flunarizine has good clinical curative effect in treatment of vertebrobasilar insufficiency vertigo with less adverse reactions, which has a certain clinical application value.