目的 探討枳術寬中膠囊聯(lián)合紅霉素治療功能性消化不良的臨床療效。方法 選取2015年8月-2017年5月北京市門頭溝區(qū)中醫(yī)醫(yī)院收治的116例功能性消化不良患者，隨機分為對照組和治療組，每組各58例。對照組口服紅霉素片，0.5 g/次，2次/d。治療組在對照組治療基礎上口服枳術寬中膠囊，3粒/次，3次/d。兩組7 d為1個療程，均連用4個療程。觀察兩組的臨床療效，比較兩組治療前后臨床癥狀積分、胃半排空時間、血清胃動素（MTL）、生長抑素（SS）的變化情況。結(jié)果 治療后，對照組和治療組的總有效率分別為77.59%、96.55%，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，兩組臨床癥狀積分顯著下降，兩組胃半排空時間均有顯著縮短，同組治療前后差異有統(tǒng)計學意義（P<0.05）；治療后，治療組的臨床癥狀積分、胃半排空時間均明顯低于對照組，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療后，兩組血清MTL水平均有顯著升高，SS水平顯著降低，同組治療前后差異有統(tǒng)計學意義（P<0.05）；但與對照組相比，治療后治療組血清MTL、SS指標改善更明顯，兩組比較差異有統(tǒng)計學意義（P<0.05）。結(jié)論 枳術寬中膠囊聯(lián)合紅霉素治療功能性消化不良具有較好的臨床療效，可調(diào)節(jié)胃腸激素分泌，加快胃腸排空，且藥物使用安全性高，具有一定的臨床推廣應用價值。

Objective To investigate the clinical efficacy of Zhizhu Kuanzhong Capsules combined with erythromycin in treatment of functional dyspepsia. Methods Patients (116 cases) with functional dyspepsia in Beijing Mentougou District Hospital of Traditional Chinese Medicine from August 2015 to May 2017 were randomly divided into control (58 cases) and treatment (58 cases) groups. Patients in the control group were po administered with Erythromycin Tablets, 0.5 g/time, twice daily. Patients in the treatment group were po administered with Zhizhu Kuanzhong Capsules on the basis of the control group, 3 grains/time, three times daily. 7 Days was as one course of treatment. Patients in two groups were treated for four courses. After treatment, the clinical efficacy was evaluated, and the changes of clinical symptom integral, gastric emptying time, MTL and SS in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 77.59% and 96.55%, respectively, and there was difference between two groups (P<0.05). After treatment, clinical symptom integral decreased statistically, and gastric emptying time shortened significantly, and the difference was statistically significant in the same group (P<0.05). After treatment, clinical symptom integral and gastric emptying time in the treatment group was lower than those in the control groups, and there was difference between two groups (P<0.05). After treatment, the level of MTL in two groups increased statistically, but the level of SS in two group decreased statistically, and the difference was statistically significant in the same group (P<0.05). After treatment, MTL and SS in the treatment group improved obviously, and there was difference between two groups (P<0.05). Conclusion Zhizhu Kuanzhong Capsules combined with erythromycin has a significant effect in treatment of functional dyspepsia, and can regulate the secretion of gastrointestinal hormones, also can accelerate gastric emptying with high safety, which has a certain clinical application value.