目的 調(diào)查宜昌市第一人民醫(yī)院產(chǎn)科圍手術(shù)期抗菌藥物的使用情況，為臨床合理應(yīng)用抗菌藥物提供參考。方法 選取宜昌市人民醫(yī)院2014年1月—2016年9月產(chǎn)科收治的800例患者為研究對(duì)象，對(duì)其在圍手術(shù)期抗菌藥物的使用情況進(jìn)行分析。結(jié)果 納入研究的患者年齡以18～35歲為主，使用較多的抗菌藥物為頭孢菌素類，其中以五水頭孢唑林鈉和頭孢替唑使用較為頻繁，使用率分別為64.61%、49.40%；單一用藥為主，構(gòu)成比為95.25%；用藥1～3 d內(nèi)的僅有146例，占18.25%；使用預(yù)防類藥物的有716例，占總數(shù)的89.5%。結(jié)論 宜昌市第一人民醫(yī)院產(chǎn)科圍手術(shù)期抗菌藥物的使用基本合理，僅有少數(shù)藥物的選擇不恰當(dāng)以及預(yù)防用藥的時(shí)間相對(duì)較長等問題，需要進(jìn)一步加強(qiáng)抗菌藥物的管理和使用。

Objective To investigate the usage of perioperative antibiotics in Department of Obstetrics of the First People's Hospital of Yichang, and provide reference for clinical rational use of antibiotics. Methods Patients (800 cases) were selected as participants in Department of Obstetrics of the First People's Hospital of Yichang from January 2014 to September 2016, and the usage of perioperative antibiotics were analyzed. Results The more patients were focused on 18-35 years old. The most use of antibiotics was cephalosporins, especially Cefazolin Sodium Pentahydrate for injection and ceftezole, and the use rate were 64.61% and 49.40%, respectively. A single drug was mostly used, and the constituent ratio was 95.25%. The patients with the course of treatment that was 1-3 d were only 146 cases (18.25%). There were 716 cases of patients using antimicrobial drugs for prevention, accounting for 89.5% of the total number. Conclusion The usage of perioperative antibiotics in Department of Obstetrics of the First People's Hospital of Yichang is rational on the whole, but there are still inappropriate choice of medicine and prolonged medication duration, which needs further efforts to strengthen the management and intervention.