目的 分析南京市第一醫(yī)院肺部吸入制劑的使用情況，為臨床合理使用提供參考。方法 對2011-2015年南京市第一醫(yī)院肺部吸入制劑的種類、用藥金額、用藥頻度（DDDs）、日均藥費（DDC）及藥品排序比（B/A）等進行統(tǒng)計和分析。結(jié)果 2011-2015年肺部吸入制劑的用藥金額均呈上升趨勢，但占總用藥金額的構(gòu)成比基本穩(wěn)定。其中用藥金額前3位的肺部吸入制劑為吸入用布地奈德混懸液、沙美特羅替卡松粉吸入劑、布地奈德福莫特羅粉吸入劑；DDDs排名前3位的肺部吸入制劑分別為沙美特羅替卡松吸入劑、吸入用布地奈德混懸液、沙丁胺醇?xì)忪F劑；沙丁胺醇?xì)忪F劑、沙美特羅替卡松吸入劑、噻托溴銨粉吸入劑的B/A較大，而吸入用異丙托溴銨溶液、吸入用布地奈德混懸液的B/A較小，其余吸入制劑的B/A基本接近1.00。DDC排名前3位的肺部吸入制劑分別為吸入用布地奈德混懸液、吸入用異丙托溴銨溶液、布地奈德福莫特羅粉吸入劑。結(jié)論 2011-2015年南京市第一醫(yī)院肺部吸入制劑總體用藥和價格結(jié)構(gòu)比較客觀合理。

Objective To investigate the application of pulmonary inhalers in Nanjing First Hospital, and to provide reference for rational drug use in clinic. Methods The utilization of pulmonary inhalers in Nanjing First Hospital from 2011 to 2015 was analyzed statistically in respects of drug types, consumption sum, DDDs, DDC, and rank ratios of total consumption and DDDs (B/A). Results Consumption sum of pulmonary inhalers had a rising trend from 2011 to 2015, but the proportions of pulmonary inhalers in the total drug use were kept stable. The top 3 drugs of consumption sum were Budesonide Suspension for inhalation, Salmeterol Xinafoate and Fluticasone Propionate Powder for inhalation, and Budesonide and Formoterol Fumarate Powder for inhalation. The top 3 drugs of DDDs were Salmeterol and Fluticasone Propionate for inhalation, Budesonide Suspension for inhalation, and Salbutamol Sulphate Aerosol. B/A values of Salbutamol Sulphate Aerosol, Salmeterol and Fluticasone Propionate for inhalation, and Tiotropium Bromide Powder for inhalation wwere high, while B/A values of Ipratropium Bromide Solution for inhalation and Budesonide Suspension for inhalation were low, and others were near 1.00. The top 3 drugs of DDC were Budesonide Suspension for inhalation, Ipratropium Bromide Solution for inhalation, and Budesonide and Formoterol Fumarate Powder for inhalation. Conclusion The overall drug use and the price structures in Nanjing First Hospital from 2011 to 2015 are reasonable.