目的 探討金剛藤膠囊聯(lián)合復(fù)方沙棘籽油栓治療宮頸炎的臨床療效。方法 選取2015年8月-2016年8月在漯河市第二人民醫(yī)院接受治療的宮頸炎患者94例，按照治療方法的差別分成對(duì)照組（47例）和治療組（47例）。對(duì)照組患者睡前于陰道內(nèi)放置復(fù)方沙棘籽油栓，1枚/次，1次/d。治療組在對(duì)照組的基礎(chǔ)上口服金剛藤膠囊，4粒/次，3次/d。兩組患者均治療8周。評(píng)價(jià)兩組患者臨床療效，比較兩組患者治療前后陰道出血時(shí)間、創(chuàng)面愈合時(shí)間以及血清炎性因子水平變化。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為74.47%、91.49%，兩組總有效率比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組患者陰道出血時(shí)間、創(chuàng)面愈合時(shí)間均顯著短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者血清白細(xì)胞介素-4（IL-4）、IL-10均顯著升高，腫瘤壞死因子-α（TNF-α）顯著降低，同組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組上述血清炎性因子水平優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 金剛藤膠囊聯(lián)合復(fù)方沙棘籽油栓治療宮頸炎效果顯著，可明顯改善患者臨床癥狀和炎癥反應(yīng)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical effect of Jingangteng Capsules combined with Compound Shajizi Oil Suppository in treatment of chronic cervicitis. Methods Patients (94 cases) with chronic cervicitis in Luohe Second People's Hospital from August 2015 to August 2016 were divided into control (47 cases) and treatment (47 cases) groups based on different treatment. Patients in the control group were given vaginal Compound Shajizi Oil Suppository at bedtime, 1 suppository/time, once daily. Patients in the treatment group were po administered with Jingangteng Capsules on the basis of the control group, 4 grains/time, three times daily. Patients in two groups were treated for 8 weeks. After treatment, the clinical efficacy was evaluated, and the time of vaginal bleeding and wound healing, and inflammatory factors in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 74.47% and 91.49%, respectively, and there was difference between two groups (P<0.05). After treatment, the time of vaginal bleeding and wound healing in the treatment was significantly shorter than that in the control group, and there was difference between two groups (P<0.05). After treatment, IL-4 and IL-10 in two groups were significantly increased, but TNF-α was significantly decreased, and the difference was statistically significant in the same group (P<0.05). And these serum inflammatory factors levels in the treatment were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Jingangteng Capsules combined with Compound Shajizi Oil Suppository has a obvious clinical effect in treatment of chronic cervicitis, and can significantly improve the clinical symptoms and inflammatory reaction, which has a certain clinical application value.