目的 探討速效救心丸聯(lián)合鹽酸地爾硫卓片治療不穩(wěn)定型心絞痛的臨床療效。方法 選取河南省煤炭總醫(yī)院2015年9月-2016年9月收治的不穩(wěn)定型心絞痛患者84例，隨機分成對照組和治療組，每組各42例。對照組患者口服鹽酸地爾硫卓片，30 mg/次，3次/d。治療組在對照組的基礎(chǔ)上口服速效救心丸，6粒/次，3次/d。兩組患者連續(xù)治療14 d。評價兩組患者的臨床療效、心絞痛癥狀以及心功能改善情況。結(jié)果 治療后，對照組和治療組的總有效率分別為80.95%和95.24%，兩組總有效率比較差異具有統(tǒng)計學意義（P<0.05）。治療后，兩組患者心絞痛發(fā)作頻率、心絞痛持續(xù)時間以及心電圖ST段位移均有明顯下降，同組治療前后比較差異具有統(tǒng)計學意義（P<0.05）；且治療組上述心絞痛癥狀明顯優(yōu)于對照組患者，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療后，兩組患者收縮壓、心率、心肌缺血總負荷以及心肌耗氧量均明顯下降，同組治療前后比較差異具有統(tǒng)計學意義（P<0.05）；且治療后治療組患者的心率、心肌缺血總負荷和心肌耗氧量明顯低于對照組患者，兩組比較差異有統(tǒng)計學意義（P<0.05）。結(jié)論 速效救心丸聯(lián)合鹽酸地爾硫卓片治療不穩(wěn)定型心絞痛在臨床療效、心絞痛癥狀、心功能指標改善情況等方面均要優(yōu)于單獨使用鹽酸地爾硫卓片，具有一定的臨床推廣應用價值。

Objective To investigate the clinical efficacy of Suxiao Jiuxin Pills combined with Diltiazem Hydrochloride Tablets in treatment of unstable angina pectoris. Methods Patients (84 cases) with unstable angina pectoris in The Coal General Hospital of Henan Province from September 2015 to September 2016 were randomly divided into control and treatment groups, and each group had 42 cases. Patients in the control group were po administered with Diltiazem Hydrochloride Tablets, 30 mg/time, three times daily. Patients in the treatment group were po administered with Suxiao Jiuxin Pills on the basis of the control group, 6 pills/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy, the change of angina pectoris symptoms and cardiac function in two groups before and after treatment were evaluated. Results After treatment, the clinical efficacies in the control and treatment groups were 80.95% and 95.24%, respectively, and there was difference between two groups (P<0.05). After treatment, attack frequency, duration, and electrocardiogram ST segment shift in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the angina pectoris symptoms in the treatment group were significantly better than that in the control group, with significant difference between two groups (P<0.05). After treatment, systolic pressure, heart rate, total ischemia burden, and myocardial oxygen consumption in two groups was significantly decreased, and there was difference in the same group (P<0.05). And heart rate, total ischemia burden, and myocardial oxygen consumption in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Suxiao Jiuxin Pills combined with Diltiazem Hydrochloride Tablets is better than the use of Diltiazem Hydrochloride Tablets alone in clinical efficacy, angina pectoris symptoms, and cardiac function in treatment of unstable angina pectoris, which has a certain clinical application value.