目的 觀察腦血疏口服液聯(lián)合神經(jīng)節(jié)苷脂治療急性腦出血的臨床療效。方法 選取2012年1月-2015年12月在連云港市贛榆區(qū)人民醫(yī)院接受急性腦出血治療的患者82例，隨機(jī)分成對(duì)照組和治療組，每組各41例。對(duì)照組患者根據(jù)出血情況靜脈滴注單唾液酸四己糖神經(jīng)節(jié)苷脂鈉注射液，50～80 mL加入到250 mL生理鹽水中，1次/d，兩周之后根據(jù)患者情況減量，維持20～40 mL/d。治療組患者在對(duì)照組的基礎(chǔ)上口服腦血疏口服液，10 mL/次，3次/d。兩組患者均連續(xù)治療1個(gè)月。比較兩組患者臨床療效、腦血腫和腦水腫量減少量、神經(jīng)功能缺損程度（NIHSS）評(píng)分、改良Barthel指數(shù)（BI）評(píng)分以及日常生活能力（ADL）評(píng)分變化。結(jié)果 治療后，對(duì)照組和治療組總有效率分別為78.05%和92.68%，兩組總有效率比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者腦血腫和腦水腫減少量均比治療前明顯減少（P<0.05）；且治療后治療組腦血腫和腦水腫減少量比對(duì)照組的更明顯（P<0.05）。治療后，兩組患者NIHSS評(píng)分比治療前明顯降低，BI和ADL評(píng)分比治療前明顯升高，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組患者上述指標(biāo)評(píng)分改善程度優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 腦血疏口服液聯(lián)合神經(jīng)節(jié)苷脂治療急性腦出血能有效減少患者腦血腫和腦水腫量，降低神經(jīng)功能缺損程度，提高改良BI，增強(qiáng)日常生活能力，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical effect of Naoxueshu Oral Liquid combined with ganglion glycoside in treatment of acute cerebral hemorrhage. Methods Patients (82 cases) with acute cerebral hemorrhage in Ganyu District People's Hospital of Lianyungang City from January 2012 to December 2015 were randomly divided into the control and treatment groups, and each group had 41 cases. The patients in the control group were iv administered with Monosialotetrahexosylganglioside Sodium Injection, 50-80 mL added into normal saline 250 mL, once daily, and the dosage was reduced according to patient's condition after 2 weeks, which maintained at 20-40 mL/d. The patients in the treatment group were po administered with Naoxueshu Oral Liquid on the basis of the control group, 10 mL/time, three times daily. Patients in two groups were treated for 1 month. After treatment, the clinical efficacy, the volume change of brain hematoma and cerebral edema, NIHSS scores, BI scores, and ADL scores in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment group were 78.05% and 92.68%, respectively, and there were differences between two groups (P<0.05). After treatment, the volume change of brain hematoma and cerebral edema in two groups were significantly decreased (P<0.05). And the volume change of brain hematoma and cerebral edema in the treatment group were decreased more obviously than those in the control group (P<0.05). After treatment, NIHSS score in two groups was decreased, but BI and ADL scores were increased, and the difference was statistically significant in the same group (P<0.05). And these observation indexes in the treatment group were better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Naoxueshu Oral Liquid combined with ganglion glycoside has effect in treatment of acute cerebral hemorrhage, can effectively reduce the volume of brain hematoma and cerebral edema and NIHSS, also improve BI and the ability of daily life, which has a certain clinical application value.