目的 探討復(fù)方聚乙二醇電解質(zhì)散（IV）聯(lián)合乳果糖口服溶液治療老年性便秘的臨床療效。方法 選取2010年12月—2016年1月內(nèi)江市第一人民醫(yī)院收治的老年性便秘患者82例，隨機(jī)分為對照組和治療組，每組各41例。對照組口服乳果糖口服溶液，15 mL/次，2次/d。治療組在對照組治療基礎(chǔ)上口服復(fù)方聚乙二醇電解質(zhì)散（IV），取本品A、B兩劑各一包，同溶于125 mL溫水中成溶液，開始時(shí)1次/d，必要時(shí)2次/d，或遵醫(yī)囑。兩組均連續(xù)治療4周。觀察兩組的臨床療效，同時(shí)比較兩組治療前后癥狀積分的變化情況。結(jié)果 治療后，對照組和治療組的總有效率分別為87.80%、95.12%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者排便程度評分、糞便性狀評分、排便時(shí)間評分均顯著降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05），且治療組這些評分的降低程度優(yōu)于對照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 復(fù)方聚乙二醇電解質(zhì)散（IV）聯(lián)合乳果糖口服溶液治療老年性便秘具有較好的臨床療效，可明顯改善臨床癥狀，安全性較為可靠，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the effect of Polyethylene Glycol Electrolytes Powder combined with Lactulose Oral Solution in treatment of senile constipation. Methods Patients (82 cases) with asthmatic diseases in the First People's Hospital of Neijiang from December 2010 to January 2016 were randomly divided into control and treatment groups. Each group had 41 cases. The patients in the control group were po administered with Lactulose Oral Solution, 15 mL/time, twice daily. The patients in the treatment group were po administered with Polyethylene Glycol Electrolytes Powder (IV) on the basis of the control group, a pack of each product A and B dissolved in warm water 125 mL, once daily at the beginning, if necessary, twice daily or as directed by physician. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies were evaluated, and the changes of symptom score in two groups before and after treatment were compared. Results After treatment, the total efficacies in the control and treatment groups were 87.80% and 95.12%, respectively, and there were differences between two groups (P<0.05). After treatment, scores of defecation degree, fecal character, and defecation time in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the decreased degrees of scores in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Polyethylene Glycol Electrolytes Powder (IV) combined with Lactulose Oral Solution has clinical curative effect in treatment of senile constipation, and can obviously improve the clinical symptoms, and security is more reliable, which has a certain clinical application value.