目的 探究三味檀香膠囊聯(lián)合替格瑞洛治療冠心病的臨床療效。方法 選取2013年1月—2015年1月在延安市人民醫(yī)院接受治療的冠心病患者94例，根據(jù)隨機數(shù)字表法分成對照組和治療組，每組各47例。對照組患者口服替格瑞洛片，起始劑量為單次負荷劑量180 mg/d，7 d后調(diào)整為90 mg/d進行維持治療。治療組在對照組基礎上口服三味檀香膠囊，3粒/次，2次/d。所有患者均治療4周。觀察兩組的臨床療效，比較治療前后兩組的超敏C-反應蛋白（hs-CRP）和白細胞介素-6（IL-6）的變化。結(jié)果 治療后，對照組和治療組的心絞痛療效總有效率分別為87.23%、95.74%，兩組比較差異有統(tǒng)計學意義（P<0.05）。治療后，兩組患者hs-CRP和IL-6的水平均顯著降低，同組治療前后差異有統(tǒng)計學意義（P<0.05）；且治療組這些觀察指標的改善程度優(yōu)于對照組，兩組比較差異具有統(tǒng)計學意義（P<0.05）。結(jié)論 三味檀香膠囊聯(lián)合替格瑞洛治療冠心病具有較好的臨床療效，能改善臨床癥狀，降低炎性因子水平，具有一定的臨床推廣應用價值。

Objective To investigate the clinical efficacy of Sanwei Tanxiang Capsules combined with ticagrelor in treatment of coronary heart disease. Methods Patients (94 cases) with cerebral infarction in Yan'an People's Hospital from January 2013 to January 2015 were divided into the control and treatment groups by random number table, and each group had 47 cases. Patients in the control group were po administered with Ticagrelor Tablets, starting dosage was 180 mg/d, and the dosage was adjusted to 90 mg/d after 7 d. Patients in the treatment group were po administered with Sanwei Tanxiang Capsules on the basis of the control group, 3 grains/time, twice daily. Patients in two groups were treated for 4 weeks. After treatment, the efficacies were evaluated, and the levels of hs-CRP and IL-6 in two groups were compared. Results After treatment, the clinical efficacies of angina pectoris in the control and treatment groups were 87.23% and 95.74%, respectively, and there was difference between two groups (P<0.05). After treatment, the levels of hs-CRP and IL-6 in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Sanwei Tanxiang Capsules combined with ticagrelor has the clinical curative effect in treatment of coronary heart disease, and can improve clinical symptoms, reduce the levels of inflammatory factors which has a certain clinical application value.