目的 調(diào)查天津市第三中心醫(yī)院2012-2014年腫瘤科住院患者麻醉藥品的使用情況和用藥趨勢,為臨床合理應(yīng)用及規(guī)范化管理麻醉藥品提供參考。方法 統(tǒng)計(jì)腫瘤科住院患者麻醉藥品的使用數(shù)據(jù),對(duì)2012-2014年麻醉藥品品種、用藥處方數(shù)、各劑型使用量、用藥頻度(DDDs)等數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。結(jié)果 2012-2014年腫瘤科麻醉藥品處方共計(jì)6860張,品規(guī)有10種,包括口服劑型6種,注射劑型3種,外用貼劑1種。麻醉藥品用量呈逐年上升趨勢,2014年用藥頻度(DDDs)排序前3位分別為嗎啡緩釋片(30mg)、嗎啡緩釋片(10mg)和鹽酸羥考酮緩釋片(10mg);嗎啡各年度用量有逐漸上升趨勢,主要用于癌性疼痛患者。結(jié)論 天津市第三中心醫(yī)院腫瘤科麻醉藥品的使用情況基本合理,基本符合"癌癥三階梯止痛指導(dǎo)原則"。

Objective To investigate the utilization and trend of narcotic drugs for inpatients in Department of Oncology of Tianjin Third Central Hospital during 2012-2014, and to provide reference for rational use and standardized management of narcotic drugs in the clinic. Methods The using data of narcotic drugs were collected, the drug types, prescriptions, utilization amount with different dosage forms, and defined daily doses (DDDs) of narcotic drugs were analyzed statistically during 2012-2014. Results The total prescriptions of narcotic drugs were 6 860 pieces during 2012-2014. There were 10 product rules, including six oral dosage forms, three injections, and one preparation for external use. The utilization amount of narcotic drugs had a tendency to increase. The top three DDDs of narcotic drugs were Sustained-release Morphine Tablets (30 mg), Sustained-release Morphine Tablets (10 mg), Oxycodone Hydrochloride Prolonged-release Tablets (10 mg). The utilization amount of morphine increased year by year, and were mainly used for patients with cancer pain. Conclusion The utilization of narcotic drugs in Department of Oncology of Tianjin Third Central Hospital is basically rational, and in line with the suggests of "three-tiered cancer pain ladder" on the whole.