目的 分析一汽總醫(yī)院Ⅰ類切口手術(shù)圍手術(shù)期預(yù)防性抗菌藥物的使用情況, 促進(jìn)臨床合理使用抗菌藥物。方法 選取2014年一汽總醫(yī)院Ⅰ類切口手術(shù)圍手術(shù)期使用的抗菌藥物進(jìn)行回顧性分析, 分別對抗菌藥物科室分布、聯(lián)用情況、抗菌藥物給藥時(shí)機(jī)、用藥療程和預(yù)防用藥情況進(jìn)行統(tǒng)計(jì)分析。結(jié)果 Ⅰ類清潔切口手術(shù)圍手術(shù)期抗菌藥物的使用率為22.0%, 預(yù)防性應(yīng)用抗菌藥物的患者主要分布于眼科和骨科, 構(gòu)成比分別為36.9%、34.8%;給藥時(shí)機(jī)主要集中于術(shù)前0.5~2 h, 有316例, 占94.9%;24 h內(nèi)停藥的有203例, 占61%;品種選擇以頭孢替唑和頭孢唑啉為主。結(jié)論 一汽總醫(yī)院Ⅰ類清潔切口手術(shù)圍手術(shù)期預(yù)防性抗菌藥物的使用基本合理。

Objective To analyze the usage of prophylactic antibacterial drugs in type I incision surgery during peroperative period in General Hospital of FAW, and to promote clinical the rational use of antibacterial drugs. Methods The usage of prophylactic antibacterial drugs in type I incision surgery during peroperative period in FAW General Hospital in 2014 were summarized retrospectively, and the department distribution, combination, medication time, course of treatment, and prophylactic usage of antibacterial drugs antibacterial types were statistically analyzed. Results The usage rate of antibiotics in type I incision surgery during peroperative period was 22.0%. The main administration departments were department of ophthalmology and orthopedics. The constituent ratio was 36.9% and 334.8%, respectively. Most medication time was 0.5 — 2 h before operation, 316 cases taking 94.9%. Patients (203 cases) stopped medication within 24 h, accounted for 61%. The highest utilization ratios of antibiotics were ceftezole and cefazolin. Conclusion The utilization of prophylactic antibacterial drugs in type I incision surgery during peroperative period in General Hospital of FAW is basically rational.