目的 調(diào)查2013年6月大連醫(yī)科大學(xué)附屬第一醫(yī)院注射用奧美拉唑鈉的使用情況,為其臨床合理應(yīng)用與管理提供參考.方法 采用回顧性調(diào)查方法調(diào)取2013年6月大連醫(yī)科大學(xué)附屬第一醫(yī)院注射用奧美拉唑鈉的病例,并制定其使用的合理性評(píng)價(jià)標(biāo)準(zhǔn),評(píng)價(jià)其臨床應(yīng)用的合理性與安全性.結(jié)果 共納入有效病例865例,符合適應(yīng)癥的608例,其中治療用藥45例,內(nèi)科預(yù)防用藥270例,外科預(yù)防用藥293例.用藥途徑合理的為238例,不合理的為160例;用藥時(shí)機(jī)合理的為70例,不合理的為328例.使用劑量合理的為379例,不合理的為19例;使用頻次合理用藥103例,不合理用藥295例.結(jié)論 大連醫(yī)科大學(xué)附屬第一醫(yī)院注射用奧美拉唑鈉的臨床應(yīng)用存在多種不合理現(xiàn)象,建議臨床各科室完善使用規(guī)范,促進(jìn)合理用藥.

Objective To investigate the usage of Omeprazole Sodium for injection in the First Affiliated Hospital of Dalian Medical University in June 2013, and to provide a reference for the clinical rational use and control of Omeprazole Sodium for injection. Methods The patients who had used Omeprazole Sodium for injection in the First Affiliated Hospital of Dalian Medical University in June 2013 were conducted retrospectively. The revaluation standard for the clinical rational use of Omeprazole Sodium for injection was developed. And the rationality and safety of the usage of Omeprazole Sodium for injection were evaluated. Results A total of 865 cases were involved, and 608 cases were conformed to the indications including 45 treatment cases, 270 prophylaxis cases and 293 surgery cases. The cases of usage of Omeprazole Sodium for injection whose route of administration was reasonable were 238, and the unreasonable cases were 160. The cases whose usage time was reasonable were 70, and the unreasonable cases were 328. There were 379 cases whose usage dose were reasonable, and 19 cases were unreasonable. The cases whose usage frequency was reasonable were 103, and the unreasonable cases were 295. Conclusion There are some unreasonable phenomena in the clinical usage of Omeprazole Sodium for injection in the First Affiliated Hospital of Dalian Medical University. Each department should improve usage specifications to promote rational drug use.