目的 探討調(diào)血脂藥物在武漢市的利用情況與發(fā)展趨勢.方法 對武漢市34家醫(yī)院2011—2013年調(diào)血脂藥物的種類、銷售金額和用藥頻度(DDDs)等進(jìn)行分析.結(jié)果 2011—2013年調(diào)血脂藥物的年度銷售總金額逐年增長,分別為5 900.90、8 129.79、11 000.38萬元,其中調(diào)血脂藥物類別前3名分別為他汀類、中藥類和貝特類.各種調(diào)血脂藥物的DDDs值排序前4名保持不變,且都是他汀類藥物,分別是阿托伐他汀鈣、辛伐他汀、普伐他汀和氟伐他汀.大部分調(diào)血脂藥物的B/A值接近1.結(jié)論 他汀類藥物占武漢市調(diào)血脂藥物市場中的主導(dǎo)地位,其中阿托伐他汀鈣是最常用的品種.

Objective To investigate the current situation and trend of the utilization of lipid-modulating agents (LMAs) in Wuhan City. Methods The utilization data including varieties, consumption sum, and DDDs of LMAs in 34 hospitals in Wuhan City from 2011 to 2013 were analyzed. Results The annual consumption sum of LMAs were 59.009 0, 81.297 9, and 110.003 8 million yuan from 2011 to 2013. The statins, Chinese medicine, and fibrates ranked the top three in LMAs. DDDs of the top four LMAs remained the same. They were all statins, and they respectively were atorvastatin calcium, simvastatin, pravastatin, and fluvastatin. B/A values of most LMAs were almost 1. Conclusion The statins occupy the predominant place among all the LMAs in Wuhan City and atorvastation calcium is the most common species.