目的 評(píng)價(jià)山東中醫(yī)藥大學(xué)第二附屬醫(yī)院中藥配方顆粒的臨床使用情況。方法 對(duì)山東中醫(yī)藥大學(xué)第二附屬醫(yī)院2010年9月1日—2013年12月31日門診中藥配方顆粒的用量、金額和處方進(jìn)行回顧性、描述性分析。結(jié)果 中藥配方顆粒的發(fā)展大體經(jīng)歷了導(dǎo)入期、增長(zhǎng)期和成熟期3個(gè)階段；中藥配方顆粒品種數(shù)（357種）僅為中藥飲片（489種）的73.01%；從藥物經(jīng)濟(jì)學(xué)的角度去評(píng)價(jià)，中藥配方顆粒的價(jià)格并不像公眾認(rèn)為的那樣高；單品種前10位合計(jì)27.42%，功效分類前10位合計(jì)92.19%；中藥配方顆粒實(shí)際應(yīng)用中更多的還是依賴處方醫(yī)師的個(gè)人經(jīng)驗(yàn)。結(jié)論 中藥配方顆粒因自身優(yōu)勢(shì)而取得了發(fā)展，但也存在等效性和價(jià)格等突出問題，開拓靈活的使用思路將是未來進(jìn)一步發(fā)展的重點(diǎn)。

Objective To evaluate the clinical use of Chinese materia medica (CMM) formula granule in Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine. Methods The CMM formula granule in Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine from September 1, 2010 to December 31, 2013 were analyzed statistically in terms of the consumptions, amounts, and prescriptions.Results The development of CMM formula granule generally experienced three phases: emergence, growth, and maturity. The number of CMM formula granule (357 species) was only 73.01% of CMM decoction pieces (489 species). From the perspective of pharmacoeconomics evaluation, the price of CMM formula granule was not as high as the thought of public. The top 10 of single varieties and the efficacy of classification were totally 27.42% and 92.19%. The CMM formula granule in the practical application still more relies on the personal experience of prescribers. Conclusion The CMM formula granule has been developed as a result of its unique strength, yet is also hindered by several problems regarding equivalence and prices, etc. The key to its further development lies on more innovations on its use.

山東省中醫(yī)藥科技發(fā)展計(jì)劃項(xiàng)目（2013-104）；山東省藥學(xué)會(huì)臨床藥學(xué)奧賽康中青年科研資助項(xiàng)目（Sdpa-ask-201307）