目的 研究川烏氯仿部位的化學成分。方法 通過硅膠、堿性氧化鋁柱色譜進行分離純化，并根據(jù)理化性質(zhì)和波譜數(shù)據(jù)鑒定化合物的結(jié)構(gòu)。結(jié)果 分離得到9個化合物，分別鑒定為次烏頭堿（1）、金色酰胺醇酯（2）、烏頭堿（3）、松胞素B2（4）、宋果靈（5）、新烏頭堿（6）、多根烏頭堿（7）、北烏堿（8）、附子靈（9）。結(jié)論 化合物2為首次從烏頭屬植物中分離得到，化合物4為首次從植物界中分離得到。

Abstract: Objective To study the chemical constituents in chloroform fraction from the parent root of Aconitum carmichaeli. Methods The compounds were isolated by column chromatography (silica gel and alkaline alumina). Their structures were identified on the basis of physicochemical properties and spectroscopic data. Results Nine compounds were separated and identified as hypaconitine (1), aurantiamide acetate (2), aconitine (3), cytochalasin B2 (4), songorine (5), mesaconitine (6), karacoline (7), beiwutine (8), and fuziline (9). Conclusion Compound 2 is obtained from plants of Aconitum L. for the first time and compound 4 is isolated from plants for the first time.

國家重點基礎研究發(fā)展計劃（973計劃）項目（2009CB522804）