目的 觀察催產(chǎn)素聯(lián)合間苯三酚在足月妊娠引產(chǎn)過程中的安全性和有效性。方法 選擇單胎足月妊娠（孕周＞40周＋5 d），無陰道分娩禁忌癥的待產(chǎn)孕婦200例，隨機分為治療組（100例）和對照組（100例），治療組靜脈滴注0.9%生理鹽水500 mL＋催產(chǎn)素2.5 U＋間苯三酚120 mg；對照組靜脈滴注0.9%生理鹽水500 mL＋催產(chǎn)素2.5 U，兩組液體滴速均從8滴/min開始調(diào)速至出現(xiàn)有效宮縮后維持該濃度和滴速，比較兩組產(chǎn)婦促宮頸成熟情況（宮頸Bishop評分的變化）、引產(chǎn)成功率、總產(chǎn)程時間、產(chǎn)后2 h出血量及新生兒窒息情況。結(jié)果 治療組患者的促宮頸成熟總有效率、引產(chǎn)成功率均明顯高于對照組（P＜0.05）；治療組總產(chǎn)程時間，特別是第一產(chǎn)程較對照組明顯縮短（P＜0.05）；而產(chǎn)后2 h出血量和新生兒窒息情況兩組比較差異無統(tǒng)計學(xué)意義。治療組產(chǎn)婦宮頸水腫發(fā)生率明顯低于對照組（P＜0.05）。結(jié)論 催產(chǎn)素聯(lián)合間苯三酚可提高足月妊娠產(chǎn)婦的引產(chǎn)成功率，縮短總產(chǎn)程，但不影響母兒安全，值得臨床推廣應(yīng)用。

Objective To observe the clinical effects and safety of oxytocin combined with phloroglucinol used for term pregnancy induction. Methods Cases (200) of single term pregnant women（gestational weeks≥40 weeks + 5 d）without any taboo of vaginal delivery were randomly divided into the treatment (100 cases) and control (100 cases) groups. The patients in the treatment group were iv administered with physiological saline 500 mL+oxytocin 2.5 U+phloroglucinol 120 mg, while the patients in the control group were iv administered with physiological saline 500 mL+oxytocin 2.5 U. The liquid drip speed of both groups began from 8 drops/min until appearance of effective contractions, maintained the speed and concentration. The cervical maturity (the change of Bishop scoring) before and after treatment, the success rate of induction, the time of birth process, and the amount of bleeding in 2 h postpartum and incidence of neonatal asphyxia were compared between the two groups. Results The effective rate of prompt cervical maturity and success rate of induction in the treatment group were obviously higher than those in the control group (P < 0.05). The time of labor especially the time of first stage of labor in the treatment group was obviously shorter than those in the control group (P < 0.05). There was no difference in the amount of bleeding in 2 h postpartum and the incidence of neonatal asphyxia between the two groups. Conclusion Oxytocin combined with phloroglucinol could improve the success rate of term pregnancy induction and shorten the total birth process time. It is safety for mother and child, which is worthy of clinical application.