目的 觀察利凡諾和米非司酮聯(lián)合應(yīng)用于中期妊娠引產(chǎn)中的臨床療效。方法 選取2011年6月—2012年6月在牡丹江醫(yī)學(xué)院附屬第二醫(yī)院行中期引產(chǎn)的產(chǎn)婦120例，隨機分為對照組和觀察組，每組60例。其中對照組直接經(jīng)羊膜腔注射100 mg利凡諾，觀察組在注射利凡諾的基礎(chǔ)上，口服米非司酮，首次劑量50 mg，以后每12 h口服一次，25 mg/次，總劑量為150 mg。結(jié)果 觀察組的宮縮時間、胎盤排出時間、總產(chǎn)程、出血量及疼痛評分明顯均低于對照組（P＜0.05）；觀察組引產(chǎn)過程中并發(fā)癥的發(fā)生率為6.67%，對照組為30.00%，兩組比較差異有統(tǒng)計學(xué)意義（P＜0.05）。結(jié)論 利凡諾聯(lián)合米非司酮應(yīng)用于中期妊娠引產(chǎn)過程中療效較好，不僅縮短了引產(chǎn)產(chǎn)程，且患者的疼痛較輕，并發(fā)癥較少，值得在臨床上推廣應(yīng)用。

Objective To observe the effect of Rivanol combined with mifepristone on mid-term induction. Methods Patients (120 cases) who accepted mid-term induction in Second Affiliated Hospital of Mudanjiang Medical College from June 2011 to June 2012 were randomly divided into control group and observation group, and 60 cases in each group. The patients in the control group were iv administered with 100 mg Rivanol from amniotic cavity directly. The patients in the observation group were po administered with mifepristone, and the first dosage was 50 mg. Then the patients took orally 25 mg every 12 h, and the total dosage was 150 mg. Results The time of uterine contraction, placenta expulsion maternal, and total production process in the observation group were shorter than that in the control group (P < 0.05). At the same time, the amount of bleeding and pain scores were significantly lower than those in the control group (P < 0.05). The incidences of the complications in the observation and control groups were 6.67% and 30.00% with significant difference (P < 0.05). Conclusion Rivanol combined with mifepristone on the mid-term induction has a better effect with fewer complications. It could not only shorten the production process of induction, but also reduce pain of patients, which is worth the clinical promotion.