近幾十年來，陰、陽(yáng)離子檢測(cè)方法的發(fā)展非常迅速，檢測(cè)方法有了較大的改進(jìn)，同時(shí)離子種類得到很大的豐富。根據(jù)不同的藥物分析目的可選擇不同的檢測(cè)方法，以取得最好的檢測(cè)精度和靈敏度。簡(jiǎn)要地介紹了用于檢測(cè)藥物中常用的陰、陽(yáng)離子的比濁法、比色法、滴定法、離子選擇電極法、可見-紫外分光光度法、原子吸收分光光度法與色譜法等分析方法，并對(duì)今后的研究方向進(jìn)行了展望。

Detection methods of negative and positive ion were rapidly developed for several decades. The kind of ion was plenty and the detection methods were improved. In order to obtain satisfied accuracy and sensitivity, we should choose a suitable method according to difference analysis objective. This article briefly summarized the application of detection methods to negative and positive ion in drugs, such as turbidimetry, colorimetry, titration, ion-selective electrode, ultraviolet-visible spectrophotometry, atomic absorption spectrophotometry, and chromatography, and so on. Finaly, the development trends of the technology have been prospected.