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Archive > Volume 16 Issue 3 > 2024,16(3):313-326. DOI:https://doi.org/10.1016/j.chmed.2024.01.007 Prev Next

覆盆子的化學(xué)成分、藥理活性及開發(fā)策略：綜述

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Chemical composition, pharmacological activity and development strategies of Rubus chingii: A review

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    摘要:
    覆盆子既可用于食品又可用于醫(yī)藥，但尚未引起人們的廣泛關(guān)注。本文對(duì)掌葉覆盆子的化學(xué)成分、藥理作用、加工及應(yīng)用進(jìn)行綜述，為其進(jìn)一步開發(fā)提供參考。以“raspberry”、 “Rubus chingii”、 “chemical composition”、 “traditional use”、 “pharmacology” 等為關(guān)鍵詞，在中國(guó)知網(wǎng)、Web of Science、Elsevier、PubMed、X - Mol等數(shù)據(jù)庫收集近幾年相關(guān)文獻(xiàn)。藥理活性的總結(jié)表明，覆盆子藥理活性之間的關(guān)系仍不夠深入。應(yīng)針對(duì)該方向開展更深入的研究，探究其活性成分的作用機(jī)制，為覆盆子產(chǎn)業(yè)的進(jìn)一步發(fā)展提供有效參考。未來，在更多研究者的參與下，有望開發(fā)出基于覆盆子的創(chuàng)新藥物用于疾病的治療。

    Abstract:
    Raspberries are used for both food and medicine, but it has not yet attracted widespread attention. In this paper, the chemical constituen of the original plant raspberry. R. chingii is one of the new "Zhe Bawei" medicinal materials selected in 2017. ‘‘Zhe Bawei” refers to eight kinds of genuine medicinal materials in Zhejiang Province. The chemical constituents, pharmacological effects, processing, and application of Rubus chingii Hu were reviewed to provide a reference for its further development. Relevant literature in recent years was collected in databases such as China Knowledge Network, Web of Science, Elsevier, PubMed, and X-Mol, using ‘‘raspberry”, ‘‘Rubus chingii”, ‘‘traditional use”, ‘‘chemical composition”, ‘‘pharmacology”, etc. as keywords individually or in combination. The summary of pharmacological activities shows that the relationship between the pharmacological activities of raspberry is still not deep enough. More in-depth research should be carried out in this direction to explore the mechanism of action of its active ingredients and provide effective reference for the further development of the raspberry industry. In the future, with the participation of more researchers, it is expected to develop innovative drugs based on raspberry for the treatment of diseases.

    關(guān)鍵詞:
    應(yīng)用;化學(xué)成分;加工;藥理作用;覆盆子

    Keywords:


    Project Supported:
    This work was financially supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (No. ZYYCXTD-D-202005), Tianjin Municipal Science and Technology Committee (No. 20YFZCSY00560), the Key Project at Central Government Level (No. 2060302) and National Natural Science Foundation of China (No. 82373982, 82173969).

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